SGCA

Gene Symbol SGCA
Entrez Gene 6442
Alt Symbol 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
Species Human
Gene Type protein-coding
Description sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Other Description 50 kDa dystrophin-associated glycoprotein|50DAG|50kD DAG|alpha-SG|alpha-sarcoglycan|dystroglycan-2
Swissprots Q13710 Q13712 A8K3K7 A6NEB8 Q16586
Accessions CCQ42962 EAW94634 EAW94635 Q16586 AK290622 BAF83311 AK293614 BAH11547 AK300710 BAH13330 BC025702 AAH25702 DQ893777 ABM84703 F25770 L34355 AAA35510 L35853 AAA50461 L46810 AAC37583 U08895 AAA81637 XM_011525120 XP_011523422 XM_011525121 XP_011523423 XM_011525122 XP_011523424 XM_011525123 XP_011523425 XM_011525124 XP_011523426 XR_934517 NM_000023 NP_000014 NM_001135697 NP_001129169
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Location Cell membrane, sarcolemma {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
Top Pathways Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

α-sarcoglycan CRISPR/Cas9 KO Plasmid (h) - sc-403837 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan HDR Plasmid (h) - sc-403837-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan Double Nickase Plasmid (h) - sc-403837-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan Double Nickase Plasmid (h2) - sc-403837-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan CRISPR Activation Plasmid (h) - sc-403837-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan CRISPR Activation Plasmid (h2) - sc-403837-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan Lentiviral Activation Particles (h) - sc-403837-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan Lentiviral Activation Particles (h2) - sc-403837-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan siRNA (h) - sc-43416 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α-sarcoglycan shRNA Plasmid (h) - sc-43416-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α-sarcoglycan shRNA (h) Lentiviral Particles - sc-43416-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU149461 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19218 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19218 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00617 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00617

SGCA siRNA (Human) - CRH4353 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

alpha-Sarcoglycan RNAi - H00006442-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SGCA - MBS8210493 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

α-sarcoglycan CRISPR/Cas9 KO Plasmid (h2) - sc-403837-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α-sarcoglycan HDR Plasmid (h2) - sc-403837-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human SGCA (NM_000023.2) - SHH406160 from Creative biogene

Category siRNA
Species Reactivities Human

SGCA shRNA Plasmid (Human) - CHH4353 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SGCA miRNA 3'UTR clone - MiUTR3H-03142 from Creative biogene

Species Reactivities Human

SGCA miRNA 3'UTR clone - MiUTR3H-03143 from Creative biogene

Species Reactivities Human
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