SGCA

Gene Symbol SGCA
Entrez Gene 6442
Alt Symbol 50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
Species Human
Gene Type protein-coding
Description sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Other Description 50 kDa dystrophin-associated glycoprotein|50DAG|50kD DAG|alpha-SG|alpha-sarcoglycan|dystroglycan-2
Swissprots Q13710 Q13712 A8K3K7 A6NEB8 Q16586
Accessions CCQ42962 EAW94634 EAW94635 Q16586 AK290622 BAF83311 AK293614 BAH11547 AK300710 BAH13330 BC025702 AAH25702 DQ893777 ABM84703 F25770 L34355 AAA35510 L35853 AAA50461 L46810 AAC37583 U08895 AAA81637 XM_011525120 XP_011523422 XM_011525121 XP_011523423 XM_011525122 XP_011523424 XM_011525123 XP_011523425 XM_011525124 XP_011523426 XR_934517 NM_000023 NP_000014 NM_001135697 NP_001129169
Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Location Cell membrane, sarcolemma {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.
Top Pathways Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

α-sarcoglycan (F-7) - sc-390647 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-sarcoglycan (F-7): sc-390647. Western blot analysis of α-sarcoglycan expression in human skeletal muscle tissue extract.

α-sarcoglycan (D-7) - sc-271321 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
α-sarcoglycan (D-7): sc-271321. Western blot analysis of α-sarcoglycan expression in SJRH30 (A) and Hs.732.Sk/Mu (B) whole cell lysates.

α-sarcoglycan (H-82) - sc-28278 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
α-sarcoglycan (H-82): sc-28278. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vagina tissue showing cytoplasmic and membrane staining of squamous epithelial cells.

α-sarcoglycan (D-20) - sc-14172 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
α-sarcoglycan (D-20): sc-14172. Western blot analysis of α-sarcoglycan expression in non-transfected: sc-117752 (A) and human α-sarcoglycan transfected: sc-114140 (B) 293T whole cell lysates.

α-sarcoglycan (C-15) - sc-14174 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
α-sarcoglycan (C-15): sc-14174. Western blot analysis of α-sarcoglycan expression in non-transfected: sc-117750 (A) and human α-sarcoglycan transfected: sc-114140 (B) whole cell lysates.

Anti-alpha Sarcoglycan antibody - ab92522 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-alpha Sarcoglycan antibody (ab92522) at 1/500 dilutionLane 1 : Jurkat cell extractsLane 2 : HepG2 cell extractsLane 3 : HeLa cell extractsLane 4 : HeLa cell extracts with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-alpha Sarcoglycan antibody - ab130657 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-alpha Sarcoglycan antibody (ab130657) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-alpha Sarcoglycan antibody [Ad1/20A6] - ab49451 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone Ad1/20A6
Anti-alpha Sarcoglycan antibody [Ad1/20A6] (ab49451) at 1/250 dilution + Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330) at 20 µgSecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-alpha Sarcoglycan antibody [EPR14773] - ab189254 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14773
Anti-alpha Sarcoglycan antibody [EPR14773] (ab189254) at 1/10000 dilution + Human skeletal muscle lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-SGCA / DAG2 Antibody (aa217-289, clone Ad1/20A6) - LS-C182666 from LifeSpan Bioscience

Prices $560.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone Ad1/20A6

Anti-SGCA / DAG2 Antibody (aa238-266, AP) - LS-C269174 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266, APC) - LS-C269175 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266, Biotin) - LS-C269176 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266, FITC) - LS-C269177 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266, PE) - LS-C269179 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266, Azide-free, HRP) - LS-C269178 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa209-254) - LS-C313943 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa238-266) - LS-C330117 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SGCA / DAG2 Antibody (aa161-210) - LS-C119716 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa/HepG2/Jurkat cells, using SGCA Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SGCA / DAG2 Antibody (aa239-266) - LS-C158957 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SGCA Antibody western blot of 293 cell line lysates (35 ug/lane). The SGCA antibody detected the SGCA protein (arrow).

Anti-SGCA / DAG2 Antibody (clone 3C4) - LS-C198180 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C4
Western Blot analysis of SGCA expression in transfected 293T cell line by SGCA monoclonal antibody (M01), clone 3C4.Lane 1: SGCA transfected lysate(42.9 KDa).Lane 2: Non-transfected lysate.

alpha-Sarcoglycan Antibody (769109) - MAB7445 from Novus Biologicals

Prices $249.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 769109
Western Blot alpha-Sarcoglycan Antibody (769109)

alpha-Sarcoglycan Antibody - NBP1-90306 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: alpha Sarcoglycan Antibody [NBP1-90306] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400004)

alpha-Sarcoglycan Antibody (3C4) - H00006442-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C4
Western Blot: alpha Sarcoglycan Antibody (3C4) [H00006442-M01] - analysis of SGCA expression in transfected 293T cell line by SGCA monoclonal antibody (M01), clone 3C4. Lane 1: SGCA transfected lysate (42.9 KDa). Lane 2: Non-transfected lysate.

Anti-SGCA antibody produced in rabbit - SAB4502758 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SGCA: <B>Cat. No. SAB4502758</B>: Immunoblotting analysis of extracts from HeLa/HepG2/Jurkat cells, using Anti-SGCA antibody. The lane on the left was treated with the Anti-SGCA antibody. The lane on the right (negative control) was treated with both Anti-SGCA antibody and the synthesized immunogen peptide.
Search more