| Gene Symbol | CASP6 |
|---|---|
| Entrez Gene | 839 |
| Alt Symbol | MCH2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | caspase 6, apoptosis-related cysteine peptidase |
| Other Description | apoptotic protease MCH-2|caspase 6, apoptosis-related cysteine protease|caspase-6 |
| Swissprots | P55212 Q9BQE7 |
| Accessions | AAO63494 EAX06244 EAX06245 P55212 BC000305 AAH00305 BC004460 AAH04460 BM837197 DQ894589 ABM85515 EU176306 ABW03757 U20536 AAC50168 U20537 AAC50169 XM_005263271 XP_005263328 NM_001226 NP_001217 NM_032992 NP_116787 |
| Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Apoptosis |