Gene Symbol | CASP6 |
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Entrez Gene | 839 |
Alt Symbol | MCH2 |
Species | Human |
Gene Type | protein-coding |
Description | caspase 6, apoptosis-related cysteine peptidase |
Other Description | apoptotic protease MCH-2|caspase 6, apoptosis-related cysteine protease|caspase-6 |
Swissprots | P55212 Q9BQE7 |
Accessions | AAO63494 EAX06244 EAX06245 P55212 BC000305 AAH00305 BC004460 AAH04460 BM837197 DQ894589 ABM85515 EU176306 ABW03757 U20536 AAC50168 U20537 AAC50169 XM_005263271 XP_005263328 NM_001226 NP_001217 NM_032992 NP_116787 |
Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. |
Subcellular Location | Cytoplasm. |
Top Pathways | Apoptosis |
CASP6-Over-expression-Lysate - LY12240a from Abgent, a WuXi AppTec company
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CASP6 overexpression lysate - LY409793 from Acris Antibodies
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CASP6 overexpression lysate - LY429832 from Acris Antibodies
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CASP6 293 Cell Lysate - 400497 from ABBIOTEC
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Caspase-6 Overexpression Lysate (Native) - NBL1-08715 from Novus Biologicals
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caspase-6 (h): 293T Lysate - sc-175853 from Santa Cruz Biotechnology
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CASP6 Over-expression Lysate Product - GWB-48D73E from Genway Biotech
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Caspase-6 Overexpression Lysate (Denatured) - H00000839-T02 from Novus Biologicals
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CASP6-knockout Cell lysate - LC810030 from Acris Antibodies
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Panoply™ Human CASP6 Knockdown Stable Cell Line - CSC-DC002397 from Creative biogene
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Human CASP6 Knockout Cell Line-HeLa - CSC-RT0775 from Creative biogene
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CASP6 KO Cell Lysate-HeLa - CLKO-0279 from Creative biogene
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