Gene Symbol | CASP6 |
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Entrez Gene | 839 |
Alt Symbol | MCH2 |
Species | Human |
Gene Type | protein-coding |
Description | caspase 6, apoptosis-related cysteine peptidase |
Other Description | apoptotic protease MCH-2|caspase 6, apoptosis-related cysteine protease|caspase-6 |
Swissprots | P55212 Q9BQE7 |
Accessions | AAO63494 EAX06244 EAX06245 P55212 BC000305 AAH00305 BC004460 AAH04460 BM837197 DQ894589 ABM85515 EU176306 ABW03757 U20536 AAC50168 U20537 AAC50169 XM_005263271 XP_005263328 NM_001226 NP_001217 NM_032992 NP_116787 |
Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. |
Subcellular Location | Cytoplasm. |
Top Pathways | Apoptosis |
caspase-6 CRISPR/Cas9 KO Plasmid (h) - sc-402563 from Santa Cruz Biotechnology
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caspase-6 HDR Plasmid (h) - sc-402563-HDR from Santa Cruz Biotechnology
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caspase-6 Double Nickase Plasmid (h) - sc-402563-NIC from Santa Cruz Biotechnology
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caspase-6 Double Nickase Plasmid (h2) - sc-402563-NIC-2 from Santa Cruz Biotechnology
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caspase-6 CRISPR Activation Plasmid (h) - sc-402563-ACT from Santa Cruz Biotechnology
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caspase-6 CRISPR Activation Plasmid (h2) - sc-402563-ACT-2 from Santa Cruz Biotechnology
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caspase-6 Lentiviral Activation Particles (h) - sc-402563-LAC from Santa Cruz Biotechnology
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caspase-6 Lentiviral Activation Particles (h2) - sc-402563-LAC-2 from Santa Cruz Biotechnology
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caspase-6 siRNA (h) - sc-72802 from Santa Cruz Biotechnology
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caspase-6 shRNA Plasmid (h) - sc-72802-SH from Santa Cruz Biotechnology
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caspase-6 shRNA (h) Lentiviral Particles - sc-72802-V from Santa Cruz Biotechnology
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Caspase-6 RNAi - H00000839-R01 from Novus Biologicals
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Caspase-6 RNAi - H00000839-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5387 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5387 from Sigma-Aldrich
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CASP6 siRNA (Human) - CRH0593 from Cohesion Biosciences
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CASP6 - MBS8235928 from MyBioSource
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shRNA set against Human CASP6 (NM_032992.2) - SHH255001 from Creative biogene
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shRNA set against Human CASP6(NM_032992.2) - SHG142753 from Creative biogene
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shRNA set against Human CASP6(NM_001226.3) - SHG142863 from Creative biogene
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shRNA set against Human CASP6(NM_032992.2) - SHG142881 from Creative biogene
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CASP6 shRNA Plasmid (Human) - CHH0593 from Cohesion Biosciences
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CASP6 miRNA 3'UTR clone - MiUTR1H-01686 from Creative biogene
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CASP6 miRNA 3'UTR clone - MiUTR1H-01687 from Creative biogene
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