Gene Symbol | CASP6 |
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Entrez Gene | 839 |
Alt Symbol | MCH2 |
Species | Human |
Gene Type | protein-coding |
Description | caspase 6, apoptosis-related cysteine peptidase |
Other Description | apoptotic protease MCH-2|caspase 6, apoptosis-related cysteine protease|caspase-6 |
Swissprots | P55212 Q9BQE7 |
Accessions | AAO63494 EAX06244 EAX06245 P55212 BC000305 AAH00305 BC004460 AAH04460 BM837197 DQ894589 ABM85515 EU176306 ABW03757 U20536 AAC50168 U20537 AAC50169 XM_005263271 XP_005263328 NM_001226 NP_001217 NM_032992 NP_116787 |
Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. |
Subcellular Location | Cytoplasm. |
Top Pathways | Apoptosis |
Active human Caspase-6 full length protein - ab52157 from Abcam
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Active human Caspase-6 full length protein - ab198067 from Abcam
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Caspase-6 peptide - ab38263 from Abcam
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E2217 from LifeSpan Bioscience
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E2746 from LifeSpan Bioscience
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E30124 from LifeSpan Bioscience
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E30125 from LifeSpan Bioscience
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E7250 from LifeSpan Bioscience
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CASP6 / Caspase 6 Antibody Blocking Peptide - LS-E21587 from LifeSpan Bioscience
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Recombinant Human Caspase-6 Protein - H00000839-Q01 from Novus Biologicals
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Caspase-6 Recombinant Protein - P4037 from Novus Biologicals
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Caspase-6 Blocking Peptide - NBP1-76609PEP from Novus Biologicals
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Caspase-6 Protein - NBP1-99217 from Novus Biologicals
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Recombinant Human Caspase-6 Protein - NBP1-99589 from Novus Biologicals
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Caspase-6 Peptide - P0334 from Novus Biologicals
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Caspase-6 Peptide - P1283 from Novus Biologicals
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CASP6-Antibody-S257-Blocking-Peptide - BP1313d from Abgent, a WuXi AppTec company
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CASP6-Antibody-C-term-Blocking-Peptide - BP1313b from Abgent, a WuXi AppTec company
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CASP6-Antibody-N-term-Blocking-peptide - BP13835a from Abgent, a WuXi AppTec company
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Phospho-Caspase-6S257-Antibody-Blocking-peptide - BP3043a from Abgent, a WuXi AppTec company
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Caspase-6 Inhibitor Z-VEID-FMK - FMK006 from R&D Systems
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CASP6 peptide - orb217011 from Biorbyt
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CASP6 peptide - orb217010 from Biorbyt
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CASP6 Blocking Peptide - 33R-7456 from Fitzgerald
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Caspase 6 Blocking Peptide - 33R-10689 from Fitzgerald
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