UBAC1

Gene Symbol UBAC1
Entrez Gene 10422
Alt Symbol GBDR1, UBADC1
Species Human
Gene Type protein-coding
Description UBA domain containing 1
Other Description E3 ubiquitin-protein ligase subunit KPC2|UBA domain-containing protein 1|glialblastoma cell differentiation-related protein 1|kip1 ubiquitination-promoting complex protein 2|putative glialblastoma cell differentiation-related protein|ubiquitin associated domain containing 1|ubiquitin-associated domain-containing protein 1
Swissprots O75500 Q9UMW7 Q9BSL1
Accessions EAW88187 EAW88188 EAW88189 EAW88190 Q9BSL1 AF038200 AF068195 AAC21559 AF176796 AAD51084 BC004967 AAH04967 BC011822 AAH11822 BX647463 DQ892567 ABM83493 DQ895782 ABM86708 NM_016172 NP_057256
Function Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. {ECO:0000269|PubMed:15531880, ECO:0000269|PubMed:15746103}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10857748, ECO:0000269|PubMed:15531880}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10857748}.

GBDR1 (C-15) - sc-242887 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-KPC2 antibody - ab61596 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KPC2 antibody (ab61596) at 1 µg/ml + Liver (Human) Tissue Lysate - adult normal tissue (ab29889) at 10 µgSecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution

Anti-KPC2 antibody - ab151317 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KPC2 antibody (ab151317) at 1/1000 dilution + A549 cell lysate at 30 µg

Anti-KPC2 antibody - ab88823 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-KPC2 antibody (ab88823) at 1/500 dilution + Human liver lysate at 25 µg

Anti-KPC2 antibody - ab138287 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-KPC2 antibody (ab138287) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-KPC2 antibody - ab195600 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KPC2 antibody (ab195600) at 1/500 dilutionLane 1 : A549 cell lysateLane 2 : K562 cell lysateLane 3 : HT-29 cell lysateLane 4 : 293T cell lysateLane 5 : Human fetal liver lysate

Anti-UBAC1 / KPC2 Antibody (Arg126) - LS-C193166 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, Biotin) - LS-C272839 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, APC) - LS-C272838 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, AP) - LS-C272836 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, FITC) - LS-C272840 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, Azide-free, HRP) - LS-C272841 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa264-292, PE) - LS-C272842 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa100-150) - LS-C290766 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa77-126) - LS-C292210 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa272-302) - LS-C326123 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UBAC1 / KPC2 Antibody (aa91-140) - LS-C120453 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from 293/HUVEC cells, using UBAC1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-UBAC1 / KPC2 Antibody (aa22-71) - LS-C205827 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UBAC1 / KPC2 antibody Western Blot of Fetal Brain. Antibody dilution: 1 ug/ml.

Anti-UBAC1 / KPC2 Antibody (aa325-375) - LS-C290764 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse UBAC1 by Western Blot. Samples: Whole cell lysate (50 ug) from 293T, HeLa, Jurkat, and mouse TCMK-1 cells. Antibodies: Affinity purified rabbit anti-UBAC1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-UBAC1 / KPC2 Antibody (aa264-292) - LS-C160368 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UBAC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

UBAC1 Antibody - NBP1-81842 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBAC1 Antibody [NBP1-81842] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

UBAC1 Antibody - NBP2-15153 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UBAC1 Antibody [NBP2-15153] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE; antibody diluted at 1:1000.

Anti-UBAC1 (376-390) antibody produced in rabbit - U8633 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-UBAC1 (376-390): <B>Cat. No. U8633</B>: Immunofluorescence of HUVEC cells using UBAC1 (376-390) (RB),<B>Cat. No. U8633</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-UBAC1 antibody produced in rabbit - HPA005651 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-UBAC1: <B>Cat. No. HPA005651</B>: Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Anti-UBADC1 antibody produced in mouse - SAB1400383 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-UBADC1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400383</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~45.338 kDa using human liver lysate.
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