| Gene Symbol |
UBAC1
|
| Entrez Gene |
10422
|
| Alt Symbol |
GBDR1, UBADC1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UBA domain containing 1
|
| Other Description |
E3 ubiquitin-protein ligase subunit KPC2|UBA domain-containing protein 1|glialblastoma cell differentiation-related protein 1|kip1 ubiquitination-promoting complex protein 2|putative glialblastoma cell differentiation-related protein|ubiquitin associated domain containing 1|ubiquitin-associated domain-containing protein 1
|
| Swissprots |
O75500 Q9UMW7 Q9BSL1
|
| Accessions |
EAW88187 EAW88188 EAW88189 EAW88190 Q9BSL1 AF038200 AF068195 AAC21559 AF176796 AAD51084 BC004967 AAH04967 BC011822 AAH11822 BX647463 DQ892567 ABM83493 DQ895782 ABM86708 NM_016172 NP_057256
|
| Function |
Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. {ECO:0000269|PubMed:15531880, ECO:0000269|PubMed:15746103}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10857748, ECO:0000269|PubMed:15531880}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:10857748}.
|
