| Gene Symbol |
CDC25C
|
| Entrez Gene |
995
|
| Alt Symbol |
CDC25, PPP1R60
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cell division cycle 25C
|
| Other Description |
M-phase inducer phosphatase 3|dual specificity phosphatase CDC25C|mitosis inducer CDC25|phosphotyrosine phosphatase|protein phosphatase 1, regulatory subunit 60
|
| Swissprots |
Q9H2E9 Q9H2F1 P30307 D3DQB8 Q9H2E8 Q96PL3 Q9H168
|
| Accessions |
AAL05410 AAR32098 EAW62145 EAW62146 EAW62147 EAW62148 EAW62149 EAW62150 P30307 AF086323 AF277723 AAG41885 AF277724 AAG41886 AF277725 AAG41887 AF277726 AAG41888 AF312681 AAL26835 AJ304504 CAC19192 AK097710 AK301828 BAG63273 AU098899 AU125025 AW512559 BC019089 AAH19089 DB040755 DB449713 DB516402 EU832624 ACE87715 EU832697 ACE87029 M34065 AAA35666 XM_005272145 XP_005272202 XM_005272146 XP_005272203 XM_006714739 XP_006714802 XM_011543759 XP_011542061 XM_011543760 XP_011542062 XM_011543761 XP_011542063 XM_011543762 XP_011542064 XM_011543763 XP_011542065 XM_011543764 XP_011542066 NM_001287582 NP_001274511 NM_001287583 NP_001274512 NM_001790 NP_001781 NM_022809 NP_073720
|
| Function |
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. {ECO:0000269|PubMed:8119945}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:14968113, ECO:0000269|PubMed:8119945}.
|
| Top Pathways |
Cell cycle, Progesterone-mediated oocyte maturation, Oocyte meiosis, MicroRNAs in cancer
|
