CDC25C

Gene Symbol CDC25C
Entrez Gene 995
Alt Symbol CDC25, PPP1R60
Species Human
Gene Type protein-coding
Description cell division cycle 25C
Other Description M-phase inducer phosphatase 3|dual specificity phosphatase CDC25C|mitosis inducer CDC25|phosphotyrosine phosphatase|protein phosphatase 1, regulatory subunit 60
Swissprots Q9H2E9 Q9H2F1 P30307 D3DQB8 Q9H2E8 Q96PL3 Q9H168
Accessions AAL05410 AAR32098 EAW62145 EAW62146 EAW62147 EAW62148 EAW62149 EAW62150 P30307 AF086323 AF277723 AAG41885 AF277724 AAG41886 AF277725 AAG41887 AF277726 AAG41888 AF312681 AAL26835 AJ304504 CAC19192 AK097710 AK301828 BAG63273 AU098899 AU125025 AW512559 BC019089 AAH19089 DB040755 DB449713 DB516402 EU832624 ACE87715 EU832697 ACE87029 M34065 AAA35666 XM_005272145 XP_005272202 XM_005272146 XP_005272203 XM_006714739 XP_006714802 XM_011543759 XP_011542061 XM_011543760 XP_011542062 XM_011543761 XP_011542063 XM_011543762 XP_011542064 XM_011543763 XP_011542065 XM_011543764 XP_011542066 NM_001287582 NP_001274511 NM_001287583 NP_001274512 NM_001790 NP_001781 NM_022809 NP_073720
Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity. {ECO:0000269|PubMed:8119945}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14968113, ECO:0000269|PubMed:8119945}.
Top Pathways Cell cycle, Progesterone-mediated oocyte maturation, Oocyte meiosis, MicroRNAs in cancer

SignalSilence® cdc25C siRNA (Human Specific) - 6291 from Cell Signaling Technology

Category siRNA
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with control (-) or cdc25C (+) siRNA. cdc25C was detected using cdc25C antibody, and eIF4E was detected using eIF4E Antibody #9742. The cdc25C antibody confirms silencing of cdc25C expression, and the eIF4E Antibody is used to control for loading and specificity of cdc25C siRNA.

Cdc25C CRISPR/Cas9 KO Plasmid (h) - sc-400833 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C HDR Plasmid (h) - sc-400833-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C Double Nickase Plasmid (h) - sc-400833-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C Double Nickase Plasmid (h2) - sc-400833-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C CRISPR Activation Plasmid (h) - sc-400833-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C CRISPR Activation Plasmid (h2) - sc-400833-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C Lentiviral Activation Particles (h) - sc-400833-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C Lentiviral Activation Particles (h2) - sc-400833-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Cdc25C siRNA (h) - sc-35038 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cdc25C shRNA Plasmid (h) - sc-35038-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cdc25C shRNA (h) Lentiviral Particles - sc-35038-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CDC25C RNAi - H00000995-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: CDC25C RNAi [H00000995-R01V] - Analysis of CDC25C over-expressed 293 cell line. Lane 2 cotransfected with CDC25C Validated Chimera RNAi or non-transfected control. Blot probed with H00000995-M01. GAPDH (36.1 kDa) used as loading control.

CDC25C RNAi - H00000995-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CDC25C RNAi - H00000995-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® Human Phosphatase - SIHP0930 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0061 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0931 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0062 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0063 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN1399 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1400 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1233 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1400 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1233 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt
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