Gene Symbol | METAP1D |
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Entrez Gene | 254042 |
Alt Symbol | MAP 1D, MAP1D, MetAP 1D, Metap1l |
Species | Human |
Gene Type | protein-coding |
Description | methionyl aminopeptidase type 1D (mitochondrial) |
Other Description | CDS of metAP-3 within PCR fragment|MAP 1D|metAP 1D|methionine aminopeptidase 1D, mitochondrial|methionyl aminopeptidase type 1D, mitochondrial|peptidase M 1D |
Swissprots | Q6UB28 Q1WNX3 |
Accessions | CAG34354 EAX11188 EAX11189 EAX11190 EAX11191 Q6UB28 AK093827 AY374142 AAR27795 BC029123 BC113644 AAI13645 BC143913 DQ005576 AAY55948 XM_011510895 XP_011509197 XM_011510896 XP_011509198 XM_011510897 XP_011509199 XM_011510898 XP_011509200 XM_011510899 XP_011509201 NM_199227 NP_954697 |
Function | Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity). May play a role in colon tumorigenesis. {ECO:0000255|HAMAP-Rule:MF_03174, ECO:0000269|PubMed:16568094}. |
Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03174, ECO:0000269|PubMed:14532271}. |
Tissue Specificity | Overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). {ECO:0000269|PubMed:16568094}. |
Human MAP1D full length protein - ab166024 from Abcam
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Human MAP1D full length protein - ab174389 from Abcam
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MAP1D Antibody Blocking Peptide - LS-E549 from LifeSpan Bioscience
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MAP1D Antibody Blocking Peptide - LS-E24862 from LifeSpan Bioscience
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Methionine Aminopeptidase 1D/MAP1D Recombinant Protein - H00254042-P01 from Novus Biologicals
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Methionine Aminopeptidase 1D/MAP1D Protein - NBP2-23230 from Novus Biologicals
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Methionine Aminopeptidase 1D/MAP1D Recombinant Protein - P4998 from Novus Biologicals
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MAP1D-Antibody-N-term-Blocking-peptide - BP10853a from Abgent, a WuXi AppTec company
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Recombinant Human Methionine Aminopeptidase 1D, CF - 4714-ZN-020 from R&D Systems
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METAP1D protein (His tag) - 80R-3600 from Fitzgerald
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Methionine aminopeptidase 1D / MAP1D (20-335, His-tag) - AR51287PU-N from Acris Antibodies
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Methionine aminopeptidase 1D / MAP1D (20-335, His-tag) - AR51287PU-S from Acris Antibodies
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Methionine aminopeptidase 1D / MAP1D - H00254042-P01-10 from Acris Antibodies
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Methionine aminopeptidase 1D / MAP1D - H00254042-P01-25 from Acris Antibodies
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METAP1D, 20-335aa, Human, His tag, E.coli - 01-P2467 from ARP American Research Products
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Recombinant human METAP1D, His-tagged - METAP1D-2467H from Creative Biomart
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Recombinant Human METAP1D, His-tagged - METAP1D-139H from Creative Biomart
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Recombinant Human MAP1D, His tagged - MAP1D-2201H from Creative Biomart
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Human MAP1D / Methionine Aminopeptidase 1D Protein (His Tag) - 10883-H08B-20 from Sino Biological
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Recombinant Human Methionine aminopeptidase 1D, mitochondrial(METAP1D) - CSB-YP747607HU CSB-EP747607HU CSB-BP747607HU CSB-MP747607HU from Cusabio
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METAP1D, 20-335aa, Human, His tag, E.coli - ATGP2467 from ATGen
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Recombinant Human Methionine Aminopeptidase 1D Protein, CF - 4714-ZN from R&D Systems
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Recombinant Human MAP1D / Methionine Aminopeptidase 1D Protein (His tag) - PKSH031376 from Elabscience
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Human METAP1D protein - orb163445 from Biorbyt
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Human METAP1D protein - orb259743 from Biorbyt
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