Gene Symbol | GNB4 |
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Entrez Gene | 59345 |
Alt Symbol | CMTD1F |
Species | Human |
Gene Type | protein-coding |
Description | guanine nucleotide binding protein (G protein), beta polypeptide 4 |
Other Description | G protein beta-4 subunit|guanine nucleotide-binding protein subunit beta-4|transducin beta chain 4 |
Swissprots | D3DNR8 Q9HAV0 B3KMH5 |
Accessions | CAE89866 EAW78403 EAW78404 Q9HAV0 AF300648 AAG18442 AK001890 BAG50987 AK022599 AK091332 AK290571 BAF83260 AK297174 BAG59667 AK310009 BC000873 AAH00873 HG496359 HQ447876 ADQ32360 XM_005247692 XP_005247749 XM_006713721 XP_006713784 XM_011513061 XP_011511363 NM_021629 NP_067642 |
Function | Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. |
Tissue Specificity | Strongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves. {ECO:0000269|PubMed:11842130, ECO:0000269|PubMed:23434117}. |
Top Pathways | Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse |
Human G protein beta 4 full length protein - ab40639 from Abcam
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GNB4 Antibody Blocking Peptide - LS-E6392 from LifeSpan Bioscience
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GNB4 Antibody Blocking Peptide - LS-E21010 from LifeSpan Bioscience
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Recombinant Human G protein beta 4 Protein - H00059345-P01 from Novus Biologicals
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GNB4-Antibody-Center-Blocking-Peptide - BP19123c from Abgent, a WuXi AppTec company
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GNB4 Blocking Peptide - 33R-1960 from Fitzgerald
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Transducin beta chain 4 (GNB4) - H00059345-P01-10 from Acris Antibodies
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Transducin beta chain 4 (GNB4) - H00059345-P01-25 from Acris Antibodies
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GNB4 fusion protein - Ag2604 from Proteintech Group
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Recombinant Human GNB4, T7-tagged - GNB4-1537H from Creative Biomart
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Recombinant Human GNB4, GST-tagged - GNB4-13357H from Creative Biomart
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Recombinant Human Guanine nucleotide-binding protein subunit beta-4(GNB4) - CSB-YP862056HU CSB-EP862056HU CSB-BP862056HU CSB-MP862056HU from Cusabio
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G protein beta 4 Recombinant Protein Antigen - NBP2-14060PEP from Novus Biologicals
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GNB4 Protein (OPPB00497) - OPPB00497 from Aviva Systems Biology
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GNB4 Peptide, Human - M34GP06399H from Creative Peptides
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Guanine nucleotide-binding protein subunit beta-4 (GNB4), Recombinant Protein - MBS1385735 from MyBioSource
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