DYNC1LI1

Gene Symbol	DYNC1LI1
Entrez Gene	51143
Alt Symbol	DNCLI1, LIC1
Species	Human
Gene Type	protein-coding
Description	dynein, cytoplasmic 1, light intermediate chain 1
Other Description	DLC-A\|cytoplasmic dynein 1 light intermediate chain 1\|dynein light chain A\|dynein light chain-A\|dynein light intermediate chain 1, cytosolic\|dynein, cytoplasmic, light intermediate polypeptide 1
Swissprots	Q53HK7 Q9Y6G9 Q53HC8 A2RRG7
Accessions	EAW64431 EAW64432 EAW64433 Q9Y6G9 AF078849 AAD44481 AK001081 BAG50854 AK074348 AK222573 BAD96293 AK222653 BAD96373 AK293253 BAG56785 BC131620 AAI31621 BU521223 BX649189 CAE46207 DA284201 NM_016141 NP_057225
Function	Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores. {ECO:0000269\|PubMed:19229290}.
Subcellular Location	Cytoplasm {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000269\|PubMed:19229290}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269\|PubMed:19229290}.
Top Pathways	Vasopressin-regulated water reabsorption, Phagosome, Salmonella infection

DNCLI1 (H-7) - sc-514141 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

DNCLI1 (H-7): sc-514141. Western blot analysis of DNCLI1 expression in DU 145 (A), Ramos (B), MIA PaCa-2 (C), K-562 (D) and Raji (E) whole cell lysates.

DNCLI1 (K-15) - sc-102491 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

DNCLI1 (N-16) - sc-102492 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

DNCLI1 (N-16): sc-102492. Western blot analysis of DNCLI1 expression in non-transfected: sc-117752 (A) and mouse DNCLI1 transfected: sc-119812 (B) 293T whole cell lysates.

Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody - ab154251 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody (ab154251) at 1/5000 dilution + 293T whole cell lysate at 30 µg

Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody [2E8] - ab123901 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2E8

All lanes : Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody [2E8] (ab123901) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY Cytoplasmic dynein 1 light intermediate chain 1 cDNALysates/proteins at 5 µg per lane.

Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody [EPR11240] - ab157468 from Abcam

Prices	$387.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR11240

All lanes : Anti-Cytoplasmic dynein 1 light intermediate chain 1 antibody [EPR11240] (ab157468) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysateLane 3 : Fetal brain lysateLane 4 : Fetal heart lysateLane 5 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-DYNC1LI1 Antibody (clone 1B9) - LS-C115476 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1B9

Anti-DYNC1LI1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DYNC1LI1.

Anti-DYNC1LI1 Antibody (clone 1G9) - LS-C115477 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1G9

Anti-DYNC1LI1 Antibody (clone 2B6) - LS-C115547 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2B6

Immunofluorescent staining of HeLa cells using anti-DYNC1LI1 mouse monoclonal antibody.

Anti-DYNC1LI1 Antibody (aa400-450) - LS-C290851 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-DYNC1LI1 Antibody (aa369-418) - LS-C152065 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

DYNC1LI1 antibody Western Blot of Jurkat.

Anti-DYNC1LI1 Antibody (aa1-50) - LS-C290850 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human DYNC1LI1 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-DYNC1LI1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-DYNC1LI1 Antibody (clone 1C2) - LS-C115479 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1C2

Anti-DYNC1LI1 Antibody (clone 1H4) - LS-C115480 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1H4

DYNC1LI1 Antibody - NBP2-14935 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DYNC1LI1 Antibody [NBP2-14935] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE; antibody diluted at 1:5000.

DYNC1LI1 Antibody - NBP1-87972 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: DNCIC1 Antibody [NBP1-87972] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-168

Anti-DYNC1LI1 antibody produced in rabbit - SAB2701455 from Sigma-Aldrich

Prices	$326.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-DYNC1LI1: <B>Cat. No. SAB2701455</B>: Immunohistochemical analysis of paraffin-embedded U373 xenograft, using DYNC1LI1 antibody at 1:500 dilution.

Monoclonal Anti-DYNC1LI1 antibody produced in mouse - SAB4100074 from Sigma-Aldrich

Prices	$358.00
Sizes	200 µl
Host	Mouse
Clonality	Monoclonal
Clone	DYNC1LI1-B61

<B>Immunofluorescence</B><BR/>PC3 cells were fixed and permeabilized with 4% Paraformaldehyde and 0.5% Triton X-100. Fixed cells were stained with Mouse Anti-DYNC1LI1 Clone: DYNC1LI1-B61 (<B>Cat. No. SAB4100074</B>) diluted to 1:100. The antibody was developed using Goat Anti-Mouse IgG, Atto 488 conjugate. Cells were counterstained with DAPI (blue) to stain nuclei.

Anti-DYNC1LI1 antibody produced in rabbit - HPA035013 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-DYNC1LI1: <B>Cat. No. HPA035013</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

DYNC1LI1 Antibody - C-terminal region (ARP65751_P050) - ARP65751_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

DYNC1LI1 antibody - GTX120114 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DYNC1LI1 antibody used in Immunoprecipitation. GTX120114

DYNC1LI1 antibody - GTX120806 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DYNC1LI1 antibody used in Western blot. GTX120806

DYNC1LI1 antibody [1B9] - GTX84596 from GeneTex

Prices	$329.00
Sizes	100 μl
Host	Mouse
Clonality	Monoclonal
Clone	1B9

Anti-DYNC1LI1 antibody [1B9] used in Flow cytometry/FACS. GTX84596

DYNC1LI1 antibody [1C2] - GTX84593 from GeneTex

Prices	$329.00
Sizes	100 μl
Host	Mouse
Clonality	Monoclonal
Clone	1C2

Anti-DYNC1LI1 antibody [1C2] used in ICC/IF. GTX84593

DYNC1LI1 antibody [1C5] - GTX84598 from GeneTex

Prices	$329.00
Sizes	100 μl
Host	Mouse
Clonality	Monoclonal
Clone	1C5

Anti-DYNC1LI1 antibody [1C5] used in Flow cytometry/FACS. GTX84598

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