USP44

Gene Symbol USP44
Entrez Gene 84101
Alt Symbol -
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 44
Other Description deubiquitinating enzyme 44|ubiquitin carboxyl-terminal hydrolase 44|ubiquitin specific protease 44|ubiquitin thioesterase 44|ubiquitin thiolesterase 44|ubiquitin-specific-processing protease 44
Swissprots Q9H0E7 B2RDW3
Accessions EAW97540 EAW97541 EAW97542 Q9H0E7 AA101229 AK027434 AK315697 BAG38060 AL136825 CAB66759 AM392541 CAL37419 BC030704 AAH30704 BI458616 BM023146 DA092275 DB096497 DB443014 DB454726 DB456039 DB462518 DQ890845 ABM81771 DQ893999 ABM84925 EU832278 ACE87535 EU832363 ACE86848 HY021046 XM_005269172 XP_005269229 XM_005269173 XP_005269230 XM_005269174 XP_005269231 XM_006719628 XP_006719691 XM_011538800 XP_011537102 XM_011538801 XP_011537103 XM_011538802 XP_011537104 XM_011538803 XP_011537105 XM_011538804 XP_011537106 XM_011538805 XP_011537107 XM_011538806 XP_011537108 XR_944757 XR_944758 NM_001042403 NP_001035862 NM_001278393 NP_001265322 NM_032147 NP_115523 NR_125360
Function Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination. {ECO:0000269|PubMed:17443180, ECO:0000269|PubMed:22681888}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20402667}. Note=Peaks in interphase, with relatively low levels maintained throughout mitosis. {ECO:0000250}.
Tissue Specificity Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia. {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:21853124}.

USP44 (G-2) - sc-377203 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
USP44 (G-2): sc-377203. Western blot analysis of USP44 expression in c4 (A) and JAR (B) whole cell lysates.

USP44 (F-15) - sc-79329 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP44 (F-15): sc-79329. Western blot analysis of USP44 expression in non-transfected: sc-110760 (A) and human USP44 transfected: sc-158067 (B) 293 whole cell lysates.

USP44 (H-151) - sc-292324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

USP44 (N-14) - sc-79330 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP44 (N-14): sc-79330. Western blot analysis of USP44 expression in Hep G2 whole cell lysate.

USP44 (S-14) - sc-79331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-USP44 antibody - ab121872 from Abcam

Host Rabbit
Clonality Polyclonal
ab121872 at 1/20 dilution staining USP44 in Paraffin-embedded Human duodenum tissue by Immunohistochemistry.

Anti-USP44 Antibody (aa211-260) - LS-C199712 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from LOVO/NIH-3T3 cells, using USP44 Antibody. The lane on the right was incubated with synthetic peptide.

Anti-USP44 Antibody (aa420-712, clone 5C4) - LS-C336412 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5C4
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 1D6) - LS-C336413 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D6
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 5F2) - LS-C336411 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5F2
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 5B8) - LS-C336420 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5B8
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 1D7) - LS-C336415 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D7
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 4E8) - LS-C336419 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E8
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (aa420-712, clone 1C2) - LS-C336417 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C2
E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 420-712 of human USP44 (NP_115523) were separated by SDS-PAGE and immunoblotted with anti-USP44.

Anti-USP44 Antibody (N-Terminus) - LS-C345920 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Usp44 Antibody - N-terminal region in Rat Spleen cells lysate.

Anti-USP44 Antibody (aa420-712, clone 1D1) - LS-C336416 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D1
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-USP44 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-USP44 Antibody (aa420-712, clone 1A9) - LS-C336421 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A9
IHC of paraffin-embedded Human pancreas tissue using anti-USP44 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-USP44 Antibody (aa420-712, clone 1F9) - LS-C336422 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F9
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-USP44 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

USP44 Antibody - NBP1-82229 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: USP44 Antibody [NBP1-82229] - Staining of human duodenum shows distinct cytoplasmic positivity in glandular cells.

Anti-USP44 antibody produced in rabbit - SAB4503322 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-USP44: <B>Cat. No. SAB4503322</B>: Immunoblotting analysis of extracts from LOVO/NIH-3T3 cells, using Anti-USP44 antibody. The lane on the left was treated with the Anti-USP44 antibody. The lane on the right (negative control) was treated with both Anti-USP44 antibody and the synthesized immunogen peptide.

Anti-USP44 antibody produced in rabbit - HPA026543 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-USP44: <B>Cat. No. HPA026543</B>: Immunohistochemical staining of human duodenum shows distinct cytoplasmic positivity in glandular cells.

Anti-USP44 (166-180) antibody produced in rabbit - U0885 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-USP44 (166-180): <B>Cat. No. U0885</B>: Immunofluorescence of HUVEC cells using USP44 (166-180) (RB),<B>Cat. No. U0885</B> (red) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

USP44 Antibody (OAAF04415) - OAAF04415 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

USP44 Polyclonal Antibody - A5040 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

USP44 antibody - 70R-21211 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
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