Gene Symbol | TRIM56 |
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Entrez Gene | 81844 |
Alt Symbol | RNF109 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 56 |
Other Description | E3 ubiquitin-protein ligase TRIM56|RING finger protein 109|tripartite motif-containing protein 56 |
Swissprots | Q8NAC0 Q6PJS5 Q9BRZ2 Q8N2H8 Q86VT6 Q9H031 |
Accessions | EAW50193 Q9BRZ2 AK075255 BAC11500 AL512757 CAC21676 BC005847 AAH05847 BC011882 AAH11882 BC048194 AAH48194 EU446537 ABZ92066 XM_011516589 XP_011514891 NM_030961 NP_112223 |
Function | E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
tripartite motif-containing 56, ELISA Kit - MBS9318664 from MyBioSource
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Human TRIM56 ELISA Kit - E039503 from Biobool
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