Gene Symbol | TRIM56 |
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Entrez Gene | 81844 |
Alt Symbol | RNF109 |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 56 |
Other Description | E3 ubiquitin-protein ligase TRIM56|RING finger protein 109|tripartite motif-containing protein 56 |
Swissprots | Q8NAC0 Q6PJS5 Q9BRZ2 Q8N2H8 Q86VT6 Q9H031 |
Accessions | EAW50193 Q9BRZ2 AK075255 BAC11500 AL512757 CAC21676 BC005847 AAH05847 BC011882 AAH11882 BC048194 AAH48194 EU446537 ABZ92066 XM_011516589 XP_011514891 NM_030961 NP_112223 |
Function | E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
TRIM56 CRISPR/Cas9 KO Plasmid (h) - sc-406877 from Santa Cruz Biotechnology
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TRIM56 HDR Plasmid (h) - sc-406877-HDR from Santa Cruz Biotechnology
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TRIM56 Double Nickase Plasmid (h) - sc-406877-NIC from Santa Cruz Biotechnology
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TRIM56 Double Nickase Plasmid (h2) - sc-406877-NIC-2 from Santa Cruz Biotechnology
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TRIM56 CRISPR Activation Plasmid (h) - sc-406877-ACT from Santa Cruz Biotechnology
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TRIM56 CRISPR Activation Plasmid (h2) - sc-406877-ACT-2 from Santa Cruz Biotechnology
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TRIM56 Lentiviral Activation Particles (h) - sc-406877-LAC from Santa Cruz Biotechnology
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TRIM56 Lentiviral Activation Particles (h2) - sc-406877-LAC-2 from Santa Cruz Biotechnology
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TRIM56 siRNA (h) - sc-89565 from Santa Cruz Biotechnology
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TRIM56 shRNA Plasmid (h) - sc-89565-SH from Santa Cruz Biotechnology
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TRIM56 shRNA (h) Lentiviral Particles - sc-89565-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU051151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21999 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21999 from Sigma-Aldrich
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TRIM56 siRNA (Human) - CRJ3060 from Cohesion Biosciences
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TRIM56 RNAi - H00081844-R01 from Novus Biologicals
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TRIM56 - MBS8219193 from MyBioSource
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shRNA set against Human TRIM56 (NM_030961.1) - SHH434912 from Creative biogene
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shRNA set against Human TRIM56(NM_030961.1) - SHL044234 from Creative biogene
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Human TRIM56 siRNA - orb273561 from Biorbyt
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TRIM56 shRNA Plasmid (Human) - CHJ3060 from Cohesion Biosciences
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TRIM56 miRNA 3'UTR clone - MiUTR1H-10749 from Creative biogene
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