| Gene Symbol |
TRIM56
|
| Entrez Gene |
81844
|
| Alt Symbol |
RNF109
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tripartite motif containing 56
|
| Other Description |
E3 ubiquitin-protein ligase TRIM56|RING finger protein 109|tripartite motif-containing protein 56
|
| Swissprots |
Q8NAC0 Q6PJS5 Q9BRZ2 Q8N2H8 Q86VT6 Q9H031
|
| Accessions |
EAW50193 Q9BRZ2 AK075255 BAC11500 AL512757 CAC21676 BC005847 AAH05847 BC011882 AAH11882 BC048194 AAH48194 EU446537 ABZ92066 XM_011516589 XP_011514891 NM_030961 NP_112223
|
| Function |
E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN- beta following detection of pathogen- and host-derived double- stranded DNA (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|