ANKLE2

Gene Symbol ANKLE2
Entrez Gene 23141
Alt Symbol KIAA0692, LEMD7, Lem4
Species Human
Gene Type protein-coding
Description ankyrin repeat and LEM domain containing 2
Other Description LEM domain containing 7|LEM domain-containing protein 4|ankyrin repeat and LEM domain-containing protein 2
Swissprots Q96DH4 A8KAG3 Q6P6A5 O75176 B3KN97 B3KSF8 Q86XL3 Q8TAZ9
Accessions Q86XL3 AB014592 BAA31667 AK024061 BAG51259 AK025933 AK093451 BAG52720 AK293028 BAF85717 BC001530 AAH01530 BC025347 AAH25347 BC043157 AAH43157 BC062373 AAH62373 BC082962 AAH82962 DA757330 DB451935 DB453975 R59085 XM_005266159 XP_005266216 XM_005266160 XP_005266217 XM_005266161 XP_005266218 XM_006719735 XP_006719798 XM_011534787 XP_011533089 XM_011534788 XP_011533090 XM_011534789 XP_011533091 NM_015114 NP_055929
Function Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. {ECO:0000269|PubMed:22770216}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:22770216}; Single-pass type III membrane protein {ECO:0000269|PubMed:22770216}.

ANKLE2 CRISPR/Cas9 KO Plasmid (h) - sc-411675 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 HDR Plasmid (h) - sc-411675-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 Double Nickase Plasmid (h) - sc-411675-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 Double Nickase Plasmid (h2) - sc-411675-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 CRISPR Activation Plasmid (h) - sc-411675-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 CRISPR Activation Plasmid (h2) - sc-411675-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 Lentiviral Activation Particles (h) - sc-411675-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 Lentiviral Activation Particles (h2) - sc-411675-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ANKLE2 siRNA (h) - sc-95915 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ANKLE2 shRNA Plasmid (h) - sc-95915-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ANKLE2 shRNA (h) Lentiviral Particles - sc-95915-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU141061 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3167 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3167 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ANKLE2 siRNA (Human) - CRH8029 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANKLE2 - MBS8203815 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human ANKLE2 siRNA - orb268531 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANKLE2 shRNA Plasmid (Human) - CHH8029 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ANKLE2 miRNA 3'UTR clone - MiUTR3H-13446 from Creative biogene

Species Reactivities Human
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