Gene Symbol | ANKLE2 |
---|---|
Entrez Gene | 23141 |
Alt Symbol | KIAA0692, LEMD7, Lem4 |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and LEM domain containing 2 |
Other Description | LEM domain containing 7|LEM domain-containing protein 4|ankyrin repeat and LEM domain-containing protein 2 |
Swissprots | Q96DH4 A8KAG3 Q6P6A5 O75176 B3KN97 B3KSF8 Q86XL3 Q8TAZ9 |
Accessions | Q86XL3 AB014592 BAA31667 AK024061 BAG51259 AK025933 AK093451 BAG52720 AK293028 BAF85717 BC001530 AAH01530 BC025347 AAH25347 BC043157 AAH43157 BC062373 AAH62373 BC082962 AAH82962 DA757330 DB451935 DB453975 R59085 XM_005266159 XP_005266216 XM_005266160 XP_005266217 XM_005266161 XP_005266218 XM_006719735 XP_006719798 XM_011534787 XP_011533089 XM_011534788 XP_011533090 XM_011534789 XP_011533091 NM_015114 NP_055929 |
Function | Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. {ECO:0000269|PubMed:22770216}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:22770216}; Single-pass type III membrane protein {ECO:0000269|PubMed:22770216}. |
ANKLE2 (K-18) - sc-244918 from Santa Cruz Biotechnology
|
||||||||
ANKLE2 (S-17) - sc-244916 from Santa Cruz Biotechnology
|
||||||||
Anti-ANKLE2 antibody - ab105193 from Abcam
|
||||||||
Anti-ANKLE2 antibody - ab83830 from Abcam
|
||||||||
Anti-KIAA0692 / ANKLE2 Antibody (aa800-850) - LS-C289668 from LifeSpan Bioscience
|
||||||||
Anti-KIAA0692 / ANKLE2 Antibody (aa888-938) - LS-C289670 from LifeSpan Bioscience
|
||||||||
Anti-KIAA0692 / ANKLE2 Antibody (aa700-750) - LS-C289667 from LifeSpan Bioscience
|
||||||||
Anti-KIAA0692 / ANKLE2 Antibody (aa864-913) - LS-C102591 from LifeSpan Bioscience
|
||||||||
Anti-KIAA0692 / ANKLE2 Antibody (Internal) IHC-plus⢠- LS-B9601 from LifeSpan Bioscience
|
||||||||
ANKLE2 Antibody - NBP1-82970 from Novus Biologicals
|
||||||||
ANKLE2 Antibody - NBP2-15396 from Novus Biologicals
|
||||||||
ANKLE2 Antibody - NBP1-70407 from Novus Biologicals
|
||||||||
ANKLE2 Polyclonal Antibody - bs-9743R from Bioss
|
||||||||
Anti-ANKLE2 antibody produced in rabbit - HPA003602 from Sigma-Aldrich
|
||||||||
Anti-ANKLE2 antibody produced in rabbit - SAB2701489 from Sigma-Aldrich
|
||||||||
Anti-KIAA0692 antibody produced in rabbit - SAB2101249 from Sigma-Aldrich
|
||||||||
Anti-ANKLE2 antibody produced in chicken - SAB3500750 from Sigma-Aldrich
|
||||||||
KIAA0692 antibody - middle region (ARP55170_P050) - ARP55170_P050 from Aviva Systems Biology
|
||||||||
ANKLE2 antibody [N1N3] - GTX120698 from GeneTex
|
||||||||
ANKLE2 antibody - orb75698 from Biorbyt
|
||||||||
KIAA0692 antibody - 70R-3254 from Fitzgerald
|
||||||||
ANKLE2 / KIAA0692 antibody - AP43952PU-N from Acris Antibodies
|
||||||||
ANKLE2 / KIAA0692 (Center) antibody - AP55599PU-N from Acris Antibodies
|
||||||||
ANKLE2 Antibody - 6609 from ProSci
|
||||||||
KIAA0692 Antibody - 26-973 from ProSci
|