EDA

Gene Symbol	EDA
Entrez Gene	1896
Alt Symbol	ECTD1, ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, HED1, ODT1, STHAGX1, XHED, XLHED
Species	Human
Gene Type	protein-coding
Description	ectodysplasin A
Other Description	X-linked anhidroitic ectodermal dysplasia protein|ectodysplasin-A|oligodontia 1
Swissprots	Q5JUM7 Q9Y6L2 Q92838 B7ZLU2 A2A337 Q5JS00 O75910 Q9Y6L1 Q9UP77 Q9Y6L0 Q9Y6L4 B7ZLU4 Q9Y6L3 A0AUZ2
Accessions	AAB65831 AAC50678 EAX05360 EAX05361 EAX05362 Q92838 AF040628 AAC77363 AF060999 AAC36302 AF061189 AAC77371 AF061190 AAC77372 AF061191 AAC77373 AF061192 AAC77374 AF061193 AAC77375 AF061194 AAC77376 AK311532 BC126143 AAI26144 BC144049 AAI44050 BC144051 AAI44052 BE892420 BQ008767 BQ422683 BU608133 CA433299 U59228 AAC50679 XM_006724630 XP_006724693 XM_011530885 XP_011529187 NM_001005609 NP_001005609 NM_001005610 NP_001005610 NM_001005612 NP_001005612 NM_001005613 NP_001005613 NM_001399 NP_001390 NM_001005611 NM_001005614
Function	Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.
Subcellular Location	Cell membrane; Single-pass type II membrane protein.
Tissue Specificity	Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. {ECO:0000269|Ref.6}.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

EDA (C-17) - sc-18927 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EDA (H-101) - sc-366899 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

EDA (N-20) - sc-18925 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

EDA (T-21) - sc-130746 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Rabbit Clonality Polyclonal

Anti-EDA antibody - ab198022 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EDA antibody - ab125233 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDA antibody - ab84311 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EDA antibody [MM0254-3T2] - ab89401 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone MM0254-3T2

Anti-EDA antibody - Aminoterminal end - ab64748 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-EDA antibody - C-terminal - ab150464 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (Extracellular Domain, clone 174817, Biotin) - LS-C36220 from LifeSpan Bioscience Prices $650.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 174817

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, APC) - LS-C225277 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, AP) - LS-C225275 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, FITC) - LS-C225279 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, Biotin) - LS-C225278 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, PE) - LS-C225280 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa141-378, Biotin) - LS-C299322 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus, Azide-free, HRP) - LS-C225281 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa141-378, FITC) - LS-C304381 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa218-267) - LS-C80664 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (N-Terminus) - LS-C330416 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa254-269) - LS-C312715 from LifeSpan Bioscience Prices $305.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa252-301) - LS-C102110 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody (aa141-378) - LS-C293725 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-EDA / Ectodysplasin A Antibody - LS-C341498 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

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