Gene Symbol | PAIP2 |
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Entrez Gene | 51247 |
Alt Symbol | PAIP-2, PAIP2A |
Species | Human |
Gene Type | protein-coding |
Description | poly(A) binding protein interacting protein 2 |
Other Description | PABC1-interacting protein 2|PABP-interacting protein 2|polyA-binding protein-interacting protein 2|polyadenylate-binding protein-interacting protein 2 |
Swissprots | Q9H0Y5 Q49A06 B2RBI1 D3DQC6 Q9P0Q8 Q9BPZ3 |
Accessions | CAD34710 EAW62107 EAW62108 EAW62109 EAW62110 EAW62111 EAW62112 Q9BPZ3 AF151052 AAF36138 AF317675 AAK11562 AK024552 AK314672 BAG37228 AL136640 CAB66575 AM393698 CAL38574 BC001716 AAH01716 BC039337 AAH39337 BC048106 AAH48106 BC062718 AAH62718 BI552800 BI560379 BU732743 CR533489 CAG38520 DB448759 EU832282 ACE87539 EU832367 ACE86852 XM_011543428 XP_011541730 NM_001033112 NP_001028284 NM_016480 NP_057564 NR_109830 |
Function | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. {ECO:0000269|PubMed:11172725}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11172725}. |
Human PAIP2 full length protein - ab89367 from Abcam
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Human PAIP2 peptide - ab36582 from Abcam
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PAIP2 Antibody Blocking Peptide - LS-E4454 from LifeSpan Bioscience
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PAIP2 Antibody Blocking Peptide - LS-E20383 from LifeSpan Bioscience
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PAIP2 Protein - NBP1-30279 from Novus Biologicals
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PAIP2 Recombinant Protein - P3402 from Novus Biologicals
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PAIP2-Antibody-N-term-Blocking-Peptide - BP16769a from Abgent, a WuXi AppTec company
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PAIP2 Protein (OPPA02076) - OPPA02076 from Aviva Systems Biology
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Human Polyadenylate-Binding Protein-Interacting Protein 2 protein - orb81254 from Biorbyt
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PAIP2 Blocking Peptide - 33R-6129 from Fitzgerald
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PAIP2 protein (His tag) - 80R-1215 from Fitzgerald
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PAIP2 (1-127, His-tag) - AR09299PU-L from Acris Antibodies
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PAIP2 (1-127, His-tag) - AR09299PU-N from Acris Antibodies
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PAIP2 - P3402 from Acris Antibodies
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PAIP2, 1-127 aa, Human, His-tag, E.coli - 01-2186-2 from ARP American Research Products
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PAIP2 fusion protein - ag7119 from Proteintech Group
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PAIP2 Human - PRPS-755 from NeoScientific
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Recombinant Human PAIP2 Protein - BP002918-PRO-748 from Syd Labs
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PAIP2, 1-127 aa, Recombinant Protein - GWB-P1622J from Genway Biotech
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Recombinant Human Polyadenylate-Binding Protein-Interacting Protein 2 - GWB-309ED1 from Genway Biotech
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Recombinant Human PAIP2, His-tagged - PAIP2-1816H from Creative Biomart
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PAIP2 1-127 aa - CMB-249 from Reagent Proteins
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PAIP2 Human - NKX-194 from Reagent Proteins
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Recombinant Human Polyadenylate-binding protein-interacting protein 2(PAIP2) - CSB-YP859027HU CSB-EP859027HU CSB-BP859027HU CSB-MP859027HU from Cusabio
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PAIP2, 1-127aa, Human, His tag, E.coli - ATGP0416 from ATGen
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