Gene Symbol | PAIP2 |
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Entrez Gene | 51247 |
Alt Symbol | PAIP-2, PAIP2A |
Species | Human |
Gene Type | protein-coding |
Description | poly(A) binding protein interacting protein 2 |
Other Description | PABC1-interacting protein 2|PABP-interacting protein 2|polyA-binding protein-interacting protein 2|polyadenylate-binding protein-interacting protein 2 |
Swissprots | Q9H0Y5 Q49A06 B2RBI1 D3DQC6 Q9P0Q8 Q9BPZ3 |
Accessions | CAD34710 EAW62107 EAW62108 EAW62109 EAW62110 EAW62111 EAW62112 Q9BPZ3 AF151052 AAF36138 AF317675 AAK11562 AK024552 AK314672 BAG37228 AL136640 CAB66575 AM393698 CAL38574 BC001716 AAH01716 BC039337 AAH39337 BC048106 AAH48106 BC062718 AAH62718 BI552800 BI560379 BU732743 CR533489 CAG38520 DB448759 EU832282 ACE87539 EU832367 ACE86852 XM_011543428 XP_011541730 NM_001033112 NP_001028284 NM_016480 NP_057564 NR_109830 |
Function | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. {ECO:0000269|PubMed:11172725}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11172725}. |
Paip2A Antibody - 4422 from Cell Signaling Technology
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Paip2 (A-2) - sc-376970 from Santa Cruz Biotechnology
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Paip2 (H-20) - sc-18617 from Santa Cruz Biotechnology
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Paip2 (H-40) - sc-368194 from Santa Cruz Biotechnology
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Paip2 (C-8) - sc-365317 from Santa Cruz Biotechnology
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Paip2 (S-18) - sc-23582 from Santa Cruz Biotechnology
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Anti-PAIP2 antibody - C-terminal - ab200107 from Abcam
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Anti-PAIP2 Antibody - LS-C131517 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, AP) - LS-C238631 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, APC) - LS-C238633 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, FITC) - LS-C238634 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, Biotin) - LS-C238635 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, Azide-free, HRP) - LS-C248392 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34, PE) - LS-C238636 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa6-34) - LS-C323762 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (N-Terminus) - LS-C145234 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (clone AT1C12) - LS-C175819 from LifeSpan Bioscience
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Anti-PAIP2 Antibody (aa7-34) - LS-C163344 from LifeSpan Bioscience
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PAIP2 Antibody - NBP2-38802 from Novus Biologicals
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PAIP2 Antibody - NBP1-79620 from Novus Biologicals
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PAIP2 Antibody - NBP1-80954 from Novus Biologicals
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PAIP2 Antibody (1C12) - NBP2-22555 from Novus Biologicals
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PAIP2 antibody - N-terminal region (ARP56241_P050) - ARP56241_P050 from Aviva Systems Biology
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PAIP2-Antibody-N-term - AP16769a from Abgent, a WuXi AppTec company
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PAIP2 antibody [AT1C12] - GTX53755 from GeneTex
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