NOC2L

Gene Symbol NOC2L
Entrez Gene 26155
Alt Symbol NET15, NET7, NIR, PPP1R112
Species Human
Gene Type protein-coding
Description nucleolar complex associated 2 homolog (S. cerevisiae)
Other Description NOC2-like protein|novel INHAT (inhibitor of histone acetyltransferase) repressor|novel INHAT repressor|nucleolar complex protein 2 homolog|protein NOC2 homolog|protein phosphatase 1, regulatory subunit 12
Swissprots Q9Y3T9 Q5SVA3 Q9BTN6
Accessions EAW56304 EAW56305 EAW56306 Q9Y3T9 AK022756 BAB14230 AK024284 BAG51285 AK092491 BAC03905 AK225239 AK315080 AL050019 CAB43240 AM393843 CAL38718 AW749585 BC003555 AAH03555 BC009786 BX645732 DA002961 NM_015658 NP_056473
Function Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. {ECO:0000269|PubMed:16322561, ECO:0000269|PubMed:20123734, ECO:0000269|PubMed:20959462}.
Subcellular Location Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin- D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.

NOC2L (I-16) - sc-130178 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
NOC2L (I-16): sc-130178. Western blot analysis of NOC2L expression in A375 whole cell lysate.

NOC2L (K-13) - sc-165119 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NOC2L (L-14) - sc-165120 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NOC2L (L-14): sc-165120. Western blot analysis of NOC2L expression in A-375 whole cell lysate.

Anti-NOC2L antibody - ab198171 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue labeling NOC2L with ab198171 at a 1/20 dilution.

Anti-NOC2L antibody - ab75047 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOC2L antibody (ab75047) at 1/500 dilutionLane 1 : extracts from MCF-7 cellsLane 2 : extracts from MCF-7 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-NOC2L Antibody (aa602-651) - LS-C199334 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from MCF-7 cells, using NOC2L Antibody. The lane on the right was incubated with synthetic peptide.

Anti-NOC2L Antibody (C-Terminus) - LS-C345956 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of NOC2L Antibody with HeLa Whole Cell lysate.

INHAT-2 Antibody - NB100-56619 from Novus Biologicals

Prices $99.00, $229.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western Blot: INHAT-2 Antibody [NB100-56619] - Detection of INHAT-2 using this antibody at a 1:1000 dilution against 10 ug of HeLa cell lysate.

NOC2L Antibody - NBP1-92190 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NOC2L Antibody [NBP1-92190] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

NOC2L Antibody - NBP1-00953 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: NOC2L Antibody [NBP1-00953] - Western blot (WB) analysis of NOC2L (I634) antibody in extracts from MCF-7 cells.

NOC2L Polyclonal Antibody - bs-7618R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NOC2L antibody produced in rabbit - HPA044258 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NOC2L: <B>Cat. No. HPA044258</B>: Immunohistochemical staining of human cerebellum shows strong nucleolar positivity in Purkinje cells.

Anti-NOC2L (center) antibody produced in rabbit - SAB1300233 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NOC2L (Center) Antibody: <B>Cat. No. SAB1300233</B>: NOC2L in A375 cell line lysates with Anti-NOC2L (Center) Antibody at 4.0 μg/mL.

NOC2L Antibody - C-terminal region (ARP73262_P050) - ARP73262_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NOC2L antibody - GTX87980 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-NOC2L antibody used in Western blot. GTX87980

NOC2L Antibody (OAAF03957) - OAAF03957 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NOC2L (I634) - 31-B3150 from ARP American Research Products

Prices $169.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOC2L antibody - STJ94525 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

NOC2L Antibody - 36655 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Gel: 6%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds

NOC2L Antibody - E11-17146C from Enogene

Prices $225.00
Sizes 100 μg
Host Rabbit

NOC2L Antibody - C17146 from Assay Biotechnology

Prices $175.00, $275.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from MCF-7 cells, using NOC2L Antibody. The lane on the right is blocked with the synthesized peptide.

NOC2L Polyclonal Antibody - ESAP15559 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Hela cell, using NOC2L Polyclonal Antibody at dilution of 1:200

NIR Antibody - A304-530A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

Anti-NOC2L monoclonal antibody - DCABH-12594 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

NOC2L Polyclonal Antibody - PA1-41264 from Thermo Fisher Scientific

Prices $292.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Western blot detection of INHAT-2 using a INHAT-2 polyclonal antibody (Product # PA1-41264) at a 1:1000 dilution against 10 ug of HeLa cell lysate.
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