NOC2L

Gene Symbol NOC2L
Entrez Gene 26155
Alt Symbol NET15, NET7, NIR, PPP1R112
Species Human
Gene Type protein-coding
Description nucleolar complex associated 2 homolog (S. cerevisiae)
Other Description NOC2-like protein|novel INHAT (inhibitor of histone acetyltransferase) repressor|novel INHAT repressor|nucleolar complex protein 2 homolog|protein NOC2 homolog|protein phosphatase 1, regulatory subunit 12
Swissprots Q9Y3T9 Q5SVA3 Q9BTN6
Accessions EAW56304 EAW56305 EAW56306 Q9Y3T9 AK022756 BAB14230 AK024284 BAG51285 AK092491 BAC03905 AK225239 AK315080 AL050019 CAB43240 AM393843 CAL38718 AW749585 BC003555 AAH03555 BC009786 BX645732 DA002961 NM_015658 NP_056473
Function Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter. {ECO:0000269|PubMed:16322561, ECO:0000269|PubMed:20123734, ECO:0000269|PubMed:20959462}.
Subcellular Location Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Translocates from the nucleoli to the nucleoplasm in presence of several stressors like ultraviolet irradiation and actinomycin- D. Predominantly detected in the nucleoli in non-mitotic cells. Predominantly detected in nucleoplasma in cells undergoing mitosis.

NOC2L CRISPR/Cas9 KO Plasmid (h) - sc-411888 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L HDR Plasmid (h) - sc-411888-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L Double Nickase Plasmid (h) - sc-411888-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L Double Nickase Plasmid (h2) - sc-411888-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L CRISPR Activation Plasmid (h) - sc-411888-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L CRISPR Activation Plasmid (h2) - sc-411888-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L Lentiviral Activation Particles (h) - sc-411888-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L Lentiviral Activation Particles (h2) - sc-411888-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NOC2L siRNA (h) - sc-88134 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NOC2L shRNA Plasmid (h) - sc-88134-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NOC2L shRNA (h) Lentiviral Particles - sc-88134-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU105431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15390 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15390 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04078 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04078

NOC2L siRNA (Human) - CRH8739 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NOC2L (NM_015658.3) - SHH353404 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NOC2L(NM_015658.3) - SHR015016 from Creative biogene

Category siRNA
Species Reactivities Human

Human NOC2L siRNA - orb269241 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NOC2L shRNA Plasmid (Human) - CHH8739 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NOC2L miRNA 3'UTR clone - MiUTR1H-06829 from Creative biogene

Species Reactivities Human
Search more