NSMCE1

Gene Symbol	NSMCE1
Entrez Gene	197370
Alt Symbol	NSE1
Species	Human
Gene Type	protein-coding
Description	non-SMC element 1 homolog (S. cerevisiae)
Other Description	non-structural maintenance of chromosomes element 1 homolog
Swissprots	Q8WV22 Q9P045 Q9P049 D3DWF6
Accessions	EAW55754 EAW55755 EAW55756 EAW55757 EAW55758 Q8WV22 AF161451 AAF29011 AF161455 AAF29015 AK056795 AK315674 BAG38039 BC018938 AAH18938 BU685363 DB463393 XM_006721023 XP_006721086 XM_011545761 XP_011544063 XM_011545762 XP_011544064 XM_011545763 XP_011544065 NM_145080 NP_659547
Function	Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus. {ECO:0000269|PubMed:18086888, ECO:0000269|PubMed:20864041}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:18086888}. Chromosome, telomere {ECO:0000305|PubMed:18086888}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NSMCE1 full length protein - ab167918 from Abcam Category Protein Source E. coli Species Human

NSMCE1 Antibody Blocking Peptide - LS-E5820 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NSMCE1 Antibody Blocking Peptide - LS-E15970 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NSMCE1 Antibody Blocking Peptide - LS-E15969 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NSMCE1 Recombinant Protein - H00197370-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NSMCE1 Protein - NBP2-23292 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

NSMCE1-Antibody-C-term-Blocking-Peptide - BP18369b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NSMCE1 protein - orb191326 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

NSMCE1 Blocking Peptide - 33R-8094 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NSMCE1 Blocking Peptide - 33R-4454 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NSMCE1 protein (His tag) - 80R-2937 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

NSMCE1 (1-266, His-tag) - AR51055PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

NSMCE1 (1-266, His-tag) - AR51055PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

NSMCE1 - H00197370-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NSMCE1 - H00197370-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NSMCE1, 1-266aa, Human, His tag, E.coli - 01-P2231 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human NSMCE1, His-tagged - NSMCE1-29732TH from Creative Biomart Category Protein Source E. coli

Recombinant Human NSMCE1, His-tagged - NSMCE1-15875H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Non-structural maintenance of chromosomes element 1 homolog(NS - CSB-YP823886HU CSB-EP823886HU CSB-BP823886HU CSB-MP823886HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NSMCE1, 1-266aa, Human, His tag, E.coli - ATGP2231 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

NSMCE1 - TP318073 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NSMCE1 Recombinant Protein Antigen - NBP1-92201PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NSMCE1 Recombinant Protein Antigen - NBP1-92200PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NSMCE1 Peptide, Human - M34GP10648H from Creative Peptides Category Peptide Source Synthetic. Species Human

NSMCE1 - PAT-82230-1 from Nordic BioSite Category Protein Species Human

Search more