Gene Symbol | TIMP2 |
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Entrez Gene | 7077 |
Alt Symbol | CSC-21K, DDC8 |
Species | Human |
Gene Type | protein-coding |
Description | TIMP metallopeptidase inhibitor 2 |
Other Description | metalloproteinase inhibitor 2|tissue inhibitor of metalloproteinases 2 |
Swissprots | Q16121 Q9UDF7 Q93006 P16035 |
Accessions | AAC50729 AAD14025 CAR95106 CAS92764 EAW89538 EAW89539 EAW89540 EAW89541 P16035 AK294290 BAG57573 AL110197 AL713764 BC010410 BC039613 BC040039 BC040445 BC052605 AAH52605 BC071586 AAH71586 HQ448393 ADQ32873 J05593 AAA61186 M32304 AAA59581 S48568 AAB19474 X54533 CAA38400 NM_003255 NP_003246 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. {ECO:0000269|PubMed:11710594, ECO:0000269|PubMed:2554304, ECO:0000269|PubMed:2793861}. |
Subcellular Location | Secreted. |
TIMP2 293T Cell Transient Overexpression Lysate(Denatured) - H00007077-T01 from Acris Antibodies
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TIMP2 293 Cell Lysate - 408790 from ABBIOTEC
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TIMP-2 Overexpression Lysate (Native) - NBL1-16925 from Novus Biologicals
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TIMP2 Over-expression Lysate Product - GWB-EFAFA4 from Genway Biotech
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Human TIMP2 / TIMP-2 HEK293 Cell Lysate (WB positive control) - 10396-HNAHL-300 from Sino Biological
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Human TIMP2 / TIMP-2 HEK293 Cell Lysate (WB positive control) - 10396-H01HL-300 from Sino Biological
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TIMP-2 Overexpression Lysate (Denatured) - H00007077-T01 from Novus Biologicals
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Human TIMP2 Human Cells Transfected Lysate (positive control) (denatured) - orb173019 from Biorbyt
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Panoply™ Human TIMP2 Knockdown Stable Cell Line - CSC-DC015970 from Creative biogene
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