Gene Symbol | TIMP2 |
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Entrez Gene | 7077 |
Alt Symbol | CSC-21K, DDC8 |
Species | Human |
Gene Type | protein-coding |
Description | TIMP metallopeptidase inhibitor 2 |
Other Description | metalloproteinase inhibitor 2|tissue inhibitor of metalloproteinases 2 |
Swissprots | Q16121 Q9UDF7 Q93006 P16035 |
Accessions | AAC50729 AAD14025 CAR95106 CAS92764 EAW89538 EAW89539 EAW89540 EAW89541 P16035 AK294290 BAG57573 AL110197 AL713764 BC010410 BC039613 BC040039 BC040445 BC052605 AAH52605 BC071586 AAH71586 HQ448393 ADQ32873 J05593 AAA61186 M32304 AAA59581 S48568 AAB19474 X54533 CAA38400 NM_003255 NP_003246 |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. {ECO:0000269|PubMed:11710594, ECO:0000269|PubMed:2554304, ECO:0000269|PubMed:2793861}. |
Subcellular Location | Secreted. |
Active human TIMP2 full length protein - ab82117 from Abcam
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Active human TIMP2 full length protein - ab125639 from Abcam
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Human TIMP2 full length protein - ab131675 from Abcam
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Human TIMP2 full length protein - ab134440 from Abcam
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Human TIMP2 full length protein - ab151941 from Abcam
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Human TIMP2 full length protein - ab39314 from Abcam
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Human TIMP2 full length protein - ab123760 from Abcam
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Human TIMP2 full length protein - ab174037 from Abcam
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Human TIMP2 peptide - ab86642 from Abcam
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Mouse TIMP2 full length protein - ab39315 from Abcam
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Rat TIMP2 full length protein - ab39316 from Abcam
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TIMP2 peptide - ab41149 from Abcam
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TIMP2 peptide - ab41150 from Abcam
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TIMP2 peptide - ab41151 from Abcam
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TIMP2 peptide - ab45253 from Abcam
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TIMP2 Antibody Blocking Peptide - LS-E21644 from LifeSpan Bioscience
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TIMP2 Antibody Blocking Peptide - LS-E21645 from LifeSpan Bioscience
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TIMP2 Antibody Blocking Peptide - LS-E26428 from LifeSpan Bioscience
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TIMP2 Antibody Blocking Peptide - LS-E15499 from LifeSpan Bioscience
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TIMP-2 Recombinant Protein - H00007077-P01 from Novus Biologicals
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Recombinant Human TIMP-2 Protein - NBP2-22869 from Novus Biologicals
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TIMP-2 Human Expressed Protein - NBP1-99908 from Novus Biologicals
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TIMP2 Recombinant Protein (Active) - GTX48123-PRO from GeneTex
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Recombinant Human TIMP-2, CF - 971-TM-010 from R&D Systems
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Recombinant Human TIMP-2 Western Blot Standard Protein - WBC023 from R&D Systems
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