| Gene Symbol |
LTB4R
|
| Entrez Gene |
1241
|
| Alt Symbol |
BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leukotriene B4 receptor
|
| Other Description |
G protein-coupled receptor 16|G-protein coupled receptor 16|LTB4-R 1|LTB4-R1|P2Y purinoceptor 7|chemoattractant receptor-like 1|chemokine receptor-like 1|leukotriene B4 receptor 1|purinergic receptor P2Y, G-protein coupled, 7
|
| Swissprots |
Q92641 Q9BSU5 Q13305 Q53XV5 Q15722
|
| Accessions |
AAB16747 AAP84348 BAB00611 CAC42548 EAW66029 Q15722 AA021034 AW242534 BC004545 AAH04545 BQ182452 BT007267 AAP35931 BU146237 D89078 BAA20423 D89079 BAA20424 DQ893799 ABM84725 EU176177 ABW03628 U41070 AAC50628 X98356 CAA67001 NM_001143919 NP_001137391 NM_181657 NP_858043
|
| Function |
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|