Gene Symbol | LTB4R |
---|---|
Entrez Gene | 1241 |
Alt Symbol | BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
Species | Human |
Gene Type | protein-coding |
Description | leukotriene B4 receptor |
Other Description | G protein-coupled receptor 16|G-protein coupled receptor 16|LTB4-R 1|LTB4-R1|P2Y purinoceptor 7|chemoattractant receptor-like 1|chemokine receptor-like 1|leukotriene B4 receptor 1|purinergic receptor P2Y, G-protein coupled, 7 |
Swissprots | Q92641 Q9BSU5 Q13305 Q53XV5 Q15722 |
Accessions | AAB16747 AAP84348 BAB00611 CAC42548 EAW66029 Q15722 AA021034 AW242534 BC004545 AAH04545 BQ182452 BT007267 AAP35931 BU146237 D89078 BAA20423 D89079 BAA20424 DQ893799 ABM84725 EU176177 ABW03628 U41070 AAC50628 X98356 CAA67001 NM_001143919 NP_001137391 NM_181657 NP_858043 |
Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues. |
Top Pathways | Neuroactive ligand-receptor interaction |
P2Y7 CRISPR/Cas9 KO Plasmid (h) - sc-403664 from Santa Cruz Biotechnology
|
||||||||
P2Y7 HDR Plasmid (h) - sc-403664-HDR from Santa Cruz Biotechnology
|
||||||||
P2Y7 Double Nickase Plasmid (h) - sc-403664-NIC from Santa Cruz Biotechnology
|
||||||||
P2Y7 Double Nickase Plasmid (h2) - sc-403664-NIC-2 from Santa Cruz Biotechnology
|
||||||||
P2Y7 CRISPR Activation Plasmid (h) - sc-403664-ACT from Santa Cruz Biotechnology
|
||||||||
P2Y7 CRISPR Activation Plasmid (h2) - sc-403664-ACT-2 from Santa Cruz Biotechnology
|
||||||||
P2Y7 Lentiviral Activation Particles (h) - sc-403664-LAC from Santa Cruz Biotechnology
|
||||||||
P2Y7 Lentiviral Activation Particles (h2) - sc-403664-LAC-2 from Santa Cruz Biotechnology
|
||||||||
P2Y7 siRNA (h) - sc-42586 from Santa Cruz Biotechnology
|
||||||||
P2Y7 shRNA Plasmid (h) - sc-42586-SH from Santa Cruz Biotechnology
|
||||||||
P2Y7 shRNA (h) Lentiviral Particles - sc-42586-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU218781 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN12813 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12813 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR11949 from Sigma-Aldrich
|
||||||||
LTB4R siRNA (Human) - CRH0876 from Cohesion Biosciences
|
||||||||
Leukotriene B4 R1 RNAi - H00001241-R02 from Novus Biologicals
|
||||||||
shRNA set against Human LTB4R (NM_181657.3) - SHH335435 from Creative biogene
|
||||||||
LTB4R shRNA Plasmid (Human) - CHH0876 from Cohesion Biosciences
|
||||||||
LTB4R miRNA 3'UTR clone - MiUTR3H-04193 from Creative biogene
|
||||||||
LTB4R miRNA 3'UTR clone - MiUTR3H-04194 from Creative biogene
|