Gene Symbol | LTB4R |
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Entrez Gene | 1241 |
Alt Symbol | BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7 |
Species | Human |
Gene Type | protein-coding |
Description | leukotriene B4 receptor |
Other Description | G protein-coupled receptor 16|G-protein coupled receptor 16|LTB4-R 1|LTB4-R1|P2Y purinoceptor 7|chemoattractant receptor-like 1|chemokine receptor-like 1|leukotriene B4 receptor 1|purinergic receptor P2Y, G-protein coupled, 7 |
Swissprots | Q92641 Q9BSU5 Q13305 Q53XV5 Q15722 |
Accessions | AAB16747 AAP84348 BAB00611 CAC42548 EAW66029 Q15722 AA021034 AW242534 BC004545 AAH04545 BQ182452 BT007267 AAP35931 BU146237 D89078 BAA20423 D89079 BAA20424 DQ893799 ABM84725 EU176177 ABW03628 U41070 AAC50628 X98356 CAA67001 NM_001143919 NP_001137391 NM_181657 NP_858043 |
Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human Leukotriene B4 Receptor peptide - ab102095 from Abcam
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Leukotriene B4 Receptor / BLT1 Antibody Blocking Peptide - LS-E10742 from LifeSpan Bioscience
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Leukotriene B4 Receptor / BLT1 Antibody Blocking Peptide - LS-E28292 from LifeSpan Bioscience
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Leukotriene B4 Receptor / BLT1 Antibody Blocking Peptide - LS-E28293 from LifeSpan Bioscience
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Leukotriene B4 Receptor / BLT1 Antibody Blocking Peptide - LS-E28294 from LifeSpan Bioscience
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Leukotriene B4 Receptor / BLT1 Antibody Blocking Peptide - LS-E28295 from LifeSpan Bioscience
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LTB4R Blocking Peptide - 33R-1214 from Fitzgerald
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LTB4R / BLTR - H00001241-G01 from Acris Antibodies
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LTB4R / BLTR Control Peptide - SP4366CP from Acris Antibodies
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LTB4R fusion protein - Ag17558 from Proteintech Group
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Recombinant Human LTB4R - LTB4R-26799TH from Creative Biomart
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Recombinant Human LTB4R - LTB4R-27118TH from Creative Biomart
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Recombinant Human LTB4R - LTB4R-27119TH from Creative Biomart
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Recombinant Human Leukotriene B4 R1 Protein - H00001241-G01 from Novus Biologicals
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Leukotriene B4 R1 Recombinant Protein Antigen - NBP1-89959PEP from Novus Biologicals
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ChemiScreen™ BLT1 Membrane Preparation - HTS042M from EMD Millipore
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LTB4R Peptide, Human - M34GP08978H from Creative Peptides
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Leukotriene B4 receptor 1 (LTB4R), Recombinant Protein - MBS7019614 from MyBioSource
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Leukotriene B4 Receptor / BLT1 Blocking Peptide - LS-E39778 from LifeSpan Bioscience
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