MARCH5

Gene Symbol MARCH5
Entrez Gene 54708
Alt Symbol MARCH-V, MITOL, RNF153
Species Human
Gene Type protein-coding
Description membrane-associated ring finger (C3HC4) 5
Other Description E3 ubiquitin-protein ligase MARCH5|membrane-associated RING finger protein 5|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153
Swissprots Q9NX47
Accessions EAW50094 EAW50095 EAW50096 Q9NX47 AB191202 BAF02285 AK000452 BAA91173 AK294799 BAG57919 AK309175 BC015480 AAH15480 BE393612 JF432871 ADZ16088 XM_011539886 XP_011538188 NM_017824 NP_060294
Function Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1. {ECO:0000269|PubMed:16874301, ECO:0000269|PubMed:17606867, ECO:0000269|PubMed:19741096, ECO:0000269|PubMed:20103533}.
Subcellular Location Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note=Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). {ECO:0000269|PubMed:14722266, ECO:0000269|PubMed:16874301}.
Tissue Specificity Expressed in brain, heart, liver, lung, spleen, stomach, testis, skeletal and muscle. {ECO:0000269|PubMed:16874301}.

MARCH5 CRISPR/Cas9 KO Plasmid (h) - sc-404655 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 HDR Plasmid (h) - sc-404655-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 Double Nickase Plasmid (h) - sc-404655-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 Double Nickase Plasmid (h2) - sc-404655-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 CRISPR Activation Plasmid (h) - sc-404655-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 CRISPR Activation Plasmid (h2) - sc-404655-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 Lentiviral Activation Particles (h) - sc-404655-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 Lentiviral Activation Particles (h2) - sc-404655-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MARCH5 siRNA (h) - sc-90592 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCH5 shRNA Plasmid (h) - sc-90592-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MARCH5 shRNA (h) Lentiviral Particles - sc-90592-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU008921 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13034 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13034 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MARCH5 siRNA (Human) - CRJ0181 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MARCH5 RNAi - H00054708-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MARCH5 (NM_017824.4) - SHH338279 from Creative biogene

Category siRNA
Species Reactivities Human

Human MARCH5 siRNA - orb270682 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MARCH5 shRNA Plasmid (Human) - CHJ0181 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MARCH5 miRNA 3'UTR clone - MiUTR1H-06108 from Creative biogene

Species Reactivities Human
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