Gene Symbol | MARCH5 |
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Entrez Gene | 54708 |
Alt Symbol | MARCH-V, MITOL, RNF153 |
Species | Human |
Gene Type | protein-coding |
Description | membrane-associated ring finger (C3HC4) 5 |
Other Description | E3 ubiquitin-protein ligase MARCH5|membrane-associated RING finger protein 5|membrane-associated RING-CH protein V|mitochondrial ubiquitin ligase|ring finger protein 153 |
Swissprots | Q9NX47 |
Accessions | EAW50094 EAW50095 EAW50096 Q9NX47 AB191202 BAF02285 AK000452 BAA91173 AK294799 BAG57919 AK309175 BC015480 AAH15480 BE393612 JF432871 ADZ16088 XM_011539886 XP_011538188 NM_017824 NP_060294 |
Function | Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission. May play a role in the prevention of cell senescence acting as a regulator of mitochondrial quality control. Promotes ubiquitination of FIS1, DNM1L and MFN1. {ECO:0000269|PubMed:16874301, ECO:0000269|PubMed:17606867, ECO:0000269|PubMed:19741096, ECO:0000269|PubMed:20103533}. |
Subcellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note=Authors show that the protein can be detected in endoplasmic reticulum (PubMed:14722266). Authors (PubMed:16874301) show its presence only in mitochondria (PubMed:16874301). {ECO:0000269|PubMed:14722266, ECO:0000269|PubMed:16874301}. |
Tissue Specificity | Expressed in brain, heart, liver, lung, spleen, stomach, testis, skeletal and muscle. {ECO:0000269|PubMed:16874301}. |
MARCH5 (C-15) - sc-109542 from Santa Cruz Biotechnology
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MARCH5 (E-13) - sc-109543 from Santa Cruz Biotechnology
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MARCH5 (H-235) - sc-292355 from Santa Cruz Biotechnology
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Anti-MARCH5 antibody - ab77585 from Abcam
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Anti-MARCH5 Antibody (aa4-32) - LS-C164034 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, APC) - LS-C237400 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, Biotin) - LS-C237401 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, FITC) - LS-C237404 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, AP) - LS-C237402 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (aa21-70) - LS-C119932 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, Azide-free, HRP) - LS-C248766 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus, PE) - LS-C237405 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (C-Terminus) - LS-C80556 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (aa1-96) - LS-C308896 from LifeSpan Bioscience
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Anti-MARCH5 Antibody (N-Terminus) - LS-C322852 from LifeSpan Bioscience
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MARCH5 Antibody - NBP1-59585 from Novus Biologicals
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MARCH5 Antibody - NBP2-33050 from Novus Biologicals
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MARCH5 Antibody - NBP2-21583 from Novus Biologicals
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MARCH5 Antibody - H00054708-A01 from Novus Biologicals
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MARCH5 Antibody (3C3) - H00054708-M06 from Novus Biologicals
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MARCH5 Polyclonal Antibody - bs-9339R from Bioss
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Anti-41703 antibody produced in rabbit - HPA052901 from Sigma-Aldrich
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Anti-MARCH5 antibody produced in rabbit - SAB4502267 from Sigma-Aldrich
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Monoclonal Anti-MARCH5 antibody produced in mouse - WH0054708M6 from Sigma-Aldrich
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MARCH5 Antibody - N-terminal region (ARP43232_P050) - ARP43232_P050 from Aviva Systems Biology
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