Gene Symbol | BLOC1S2 |
---|---|
Entrez Gene | 282991 |
Alt Symbol | BLOS2, CEAP, CEAP11 |
Species | Human |
Gene Type | protein-coding |
Description | biogenesis of lysosomal organelles complex-1, subunit 2 |
Other Description | 11 kDa centrosome associated protein|BLOC-1 subunit 2|biogenesis of lysosome-related organelles complex 1 subunit 2|centrosomal 10 kDa protein|centrosome protein oncogene |
Swissprots | Q8WUI8 Q5W040 B4DQV2 Q6QNY1 |
Accessions | EAW49835 EAW49836 EAW49837 Q6QNY1 AB593084 BAJ84024 AK054697 AK298969 BAG61064 AY278457 AAQ19606 AY531265 AAT00461 BC020494 AAH20494 BF666010 BG545838 BG679165 BI753469 BU608851 BU740315 BX112121 CB118026 CB218039 CN340962 DB296446 DB456773 HY107885 HY165508 NM_001001342 NP_001001342 NM_001282436 NP_001269365 NM_001282437 NP_001269366 NM_001282438 NP_001269367 NM_001282439 NP_001269368 NM_173809 NP_776170 |
Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation. {ECO:0000269|PubMed:15102850, ECO:0000269|PubMed:15381421, ECO:0000269|PubMed:17182842}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15381421}. Note=Localizes to the centrosomes in a microtubule-dependent manner. |
Tissue Specificity | Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level). {ECO:0000269|PubMed:15381421}. |
Human BLOC1S2 full length protein - ab126912 from Abcam
|
||||||||||
BLOC1S2 Antibody Blocking Peptide - LS-E7879 from LifeSpan Bioscience
|
||||||||||
BLOC1S2 Recombinant Protein - H00282991-P01 from Novus Biologicals
|
||||||||||
BLOC1S2 Protein - NBP1-98999 from Novus Biologicals
|
||||||||||
BLOC1S2-Antibody-Center-Blocking-peptide - BP5538c from Abgent, a WuXi AppTec company
|
||||||||||
Human BLOC1S2 protein (GST Tag) - orb138262 from Biorbyt
|
||||||||||
Human BLOC1S2 protein - orb167986 from Biorbyt
|
||||||||||
BLOC1S2 protein (His tag) - 80R-2268 from Fitzgerald
|
||||||||||
BLOC-1 subunit 2 (1-142, His-tag) - AR50352PU-N from Acris Antibodies
|
||||||||||
BLOC-1 subunit 2 (1-142, His-tag) - AR50352PU-S from Acris Antibodies
|
||||||||||
BLOC-1 subunit 2 - H00282991-P01-10 from Acris Antibodies
|
||||||||||
BLOC-1 subunit 2 - H00282991-P01-25 from Acris Antibodies
|
||||||||||
BLOC1S2, 1-142aa, Human, His tag, E.coli - 01-P1528 from ARP American Research Products
|
||||||||||
BLOC1S2 fusion protein - Ag2807 from Proteintech Group
|
||||||||||
BLOC1S2 Human - PRPS-1101 from NeoScientific
|
||||||||||
Recombinant Human BLOC1S2 Protein - BP001569-PRO-1094 from Syd Labs
|
||||||||||
BLOC1S2, 1-142aa, Recombinant Protein - GWB-P0510C from Genway Biotech
|
||||||||||
Recombinant Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 2, His-tagged - BLOC1S2-6767H from Creative Biomart
|
||||||||||
Recombinant Human BLOC1S2, GST tagged - BLOC1S2-7382H from Creative Biomart
|
||||||||||
Recombinant Human BLOC1S2, GST-tagged - BLOC1S2-10241H from Creative Biomart
|
||||||||||
Human BLOC1S2 / BLOS2 Protein (GST Tag) - 13916-H09E-20 from Sino Biological
|
||||||||||
Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 2(BLOC1S2) - CSB-YP754307HU CSB-EP754307HU CSB-BP754307HU CSB-MP754307HU from Cusabio
|
||||||||||
BLOC1S2, 1-142aa, Human, His tag, E.coli - ATGP1528 from ATGen
|
||||||||||
BLOC1S2 Protein - abx164511 from Abbexa
|
||||||||||
BLOC-1 subunit 2 (transcript variant 2) - TP302351 from Acris Antibodies
|