BLOC1S2

Gene Symbol BLOC1S2
Entrez Gene 282991
Alt Symbol BLOS2, CEAP, CEAP11
Species Human
Gene Type protein-coding
Description biogenesis of lysosomal organelles complex-1, subunit 2
Other Description 11 kDa centrosome associated protein|BLOC-1 subunit 2|biogenesis of lysosome-related organelles complex 1 subunit 2|centrosomal 10 kDa protein|centrosome protein oncogene
Swissprots Q8WUI8 Q5W040 B4DQV2 Q6QNY1
Accessions EAW49835 EAW49836 EAW49837 Q6QNY1 AB593084 BAJ84024 AK054697 AK298969 BAG61064 AY278457 AAQ19606 AY531265 AAT00461 BC020494 AAH20494 BF666010 BG545838 BG679165 BI753469 BU608851 BU740315 BX112121 CB118026 CB218039 CN340962 DB296446 DB456773 HY107885 HY165508 NM_001001342 NP_001001342 NM_001282436 NP_001269365 NM_001282437 NP_001269366 NM_001282438 NP_001269367 NM_001282439 NP_001269368 NM_173809 NP_776170
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation. {ECO:0000269|PubMed:15102850, ECO:0000269|PubMed:15381421, ECO:0000269|PubMed:17182842}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:15381421}. Note=Localizes to the centrosomes in a microtubule-dependent manner.
Tissue Specificity Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level). {ECO:0000269|PubMed:15381421}.

BLOS2 CRISPR/Cas9 KO Plasmid (h) - sc-406776 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 HDR Plasmid (h) - sc-406776-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 Double Nickase Plasmid (h) - sc-406776-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 Double Nickase Plasmid (h2) - sc-406776-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 CRISPR Activation Plasmid (h) - sc-406776-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 CRISPR Activation Plasmid (h2) - sc-406776-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 Lentiviral Activation Particles (h) - sc-406776-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 Lentiviral Activation Particles (h2) - sc-406776-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 siRNA (h) - sc-90595 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BLOS2 shRNA Plasmid (h) - sc-90595-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BLOS2 shRNA (h) Lentiviral Particles - sc-90595-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU088661 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3991 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3991 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09731 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09731

BLOC1S2 siRNA (Human) - CRJ6859 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BLOC1S2 - MBS8216948 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BLOS2 CRISPR/Cas9 KO Plasmid (h2) - sc-406776-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BLOS2 HDR Plasmid (h2) - sc-406776-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human BLOC1S2 (NM_173809.4) - SHH246914 from Creative biogene

Category siRNA
Species Reactivities Human

Human BLOC1S2 siRNA - orb277360 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BLOC1S2 shRNA Plasmid (Human) - CHJ6859 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BLOC1S2 miRNA 3'UTR clone - MiUTR3H-10792 from Creative biogene

Species Reactivities Human
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