DEFB114

Gene Symbol DEFB114
Entrez Gene 245928
Alt Symbol DEFB-14, DEFB14
Species Human
Gene Type protein-coding
Description defensin, beta 114
Other Description beta-defensin 114|beta-defensin 14|defensin, beta 14
Swissprots Q30KQ6 Q8NES9
Accessions Q30KQ6 AY122470 AAM93912 BC156851 AAI56852 DQ012018 AAY59754 NM_001037499 NP_001032588
Function Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS- induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. {ECO:0000269|PubMed:23482568}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Expressed in epididymis, predominantly in the caput (at protein level). {ECO:0000269|PubMed:23482568}.

Anti-DEFB114 antibody - ab151158 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human kidney tissue labelling DEFB114 with ab151158 antibody at a dilution of 1/200.

DEFB114 Antibody - NBP2-14762 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DEFB114 antibody produced in rabbit - HPA052126 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DEFB114:<B>Cat. No. HPA052126</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

DEFB114 antibody (FITC) - orb187350 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

Anti-DEFB114 (aa 39-67) polyclonal antibody - DPABH-03319 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

DEFB114 antibody - orb183037 from Biorbyt

Host Rabbit
Clonality Polyclonal
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