DEFB114

Gene Symbol DEFB114
Entrez Gene 245928
Alt Symbol DEFB-14, DEFB14
Species Human
Gene Type protein-coding
Description defensin, beta 114
Other Description beta-defensin 114|beta-defensin 14|defensin, beta 14
Swissprots Q30KQ6 Q8NES9
Accessions Q30KQ6 AY122470 AAM93912 BC156851 AAI56852 DQ012018 AAY59754 NM_001037499 NP_001032588
Function Has a salt-sensitive antimicrobial activity against Gram-negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS- induced reduction of sperm motility in vitro and may protect from LPS-induced lethality. {ECO:0000269|PubMed:23482568}.
Subcellular Location Secreted {ECO:0000250}.
Tissue Specificity Expressed in epididymis, predominantly in the caput (at protein level). {ECO:0000269|PubMed:23482568}.

Recombinant Human Beta-defensin 114(DEFB114) - CSB-YP657934HU CSB-EP657934HU CSB-BP657934HU CSB-MP657934HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

DEFB114 Recombinant Protein Antigen - NBP2-14762PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Source E.coli
Species Human

Beta-defensin114 - AF2991 from Creative Peptides

Category Peptide
Source Homo sapiens

Beta-defensin 114 (DEFB114), Recombinant Protein - MBS1318807 from MyBioSource

Category Protein
Prices $765.00, $765.00, $990.00, $990.00, $1,060.00, $1,060.00, $1,515.00, $1,515.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Mouse DEFB114 Protein - NBP2-61340 from Novus Biologicals

Category Protein
Prices $179.00, $279.00, $799.00
Sizes 20 µg, 100 µg, 500 µg
Source Escherichia coli.
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