XYLT2

Gene Symbol	XYLT2
Entrez Gene	64132
Alt Symbol	PXYLT2, XT-II, XT2, xylT-II
Species	Human
Gene Type	protein-coding
Description	xylosyltransferase II
Other Description	UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase|peptide O-xylosyltransferase 1|protein xylosyltransferase 2|xylosyltransferase 2
Swissprots	Q9H1B5 Q6UY41 Q86V00
Accessions	EAW94626 EAW94627 Q9H1B5 AJ277442 CAC16788 AK299999 BAG61818 AL833210 AY358090 AAQ88457 BC017084 BC036069 BC052262 AAH52262 BC156444 AAI56445 BM726479 BQ018370 XM_005257572 XP_005257629 XM_011525114 XP_011523416 NM_022167 NP_071450 NR_110010
Function	Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated. {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Widely expressed. Expressed at higher level in kidney and pancreas. {ECO:0000269|PubMed:11099377}.
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human XYLT2 protein fragment - ab178460 from Abcam Category Protein Source HEK 293 cells Species Human

XYLT2 Antibody Blocking Peptide - LS-E6419 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

XYLT2 Antibody Blocking Peptide - LS-E17938 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

XYLT2 Antibody Blocking Peptide - LS-E17939 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

XYLT2-Antibody-N-term-Blocking-Peptide - BP19159a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

XYLT2 Blocking Peptide - 33R-7222 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

XYLT2 Blocking Peptide - 33R-5377 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant Human Xylosyltransferase 2(XYLT2) ,partial - CSB-YP884439HU CSB-EP884439HU CSB-BP884439HU CSB-MP884439HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Xylosyltransferase II (XYLT2) - RPC607Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Xylosyltransferase II (XYLT2) - RPC607Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Xylosyltransferase 2(XYLT2) ,partial, Recombinant Protein - MBS1312540 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Xylosyltransferase II (XYLT2) - RPC607Hu01 from Cloud-clone Category Protein Source E.coli Species Human

XYLT2 Peptide, Human - M34GP17606H from Creative Peptides Category Peptide Source Synthetic. Species Human

XT-2 - AF1419 from Creative Peptides Category Peptide Source Diploid clawed frog Xenopus tropicalis , Africa

Recombinant Xylosyltransferase II (XYLT2) - RPU51563 from Biomatik Category Protein Prices $176.00, $360.00, $550.00, $656.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

XYLT2 Recombinant Protein (OPCD00745) - OPCD00745 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human XYLT2 protein, His & T7-tagged - XYLT2-7937H from Creative Biomart Category Protein Source E. coli Species Human

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