XYLT2

Gene Symbol XYLT2
Entrez Gene 64132
Alt Symbol PXYLT2, XT-II, XT2, xylT-II
Species Human
Gene Type protein-coding
Description xylosyltransferase II
Other Description UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase|peptide O-xylosyltransferase 1|protein xylosyltransferase 2|xylosyltransferase 2
Swissprots Q9H1B5 Q6UY41 Q86V00
Accessions EAW94626 EAW94627 Q9H1B5 AJ277442 CAC16788 AK299999 BAG61818 AL833210 AY358090 AAQ88457 BC017084 BC036069 BC052262 AAH52262 BC156444 AAI56445 BM726479 BQ018370 XM_005257572 XP_005257629 XM_011525114 XP_011523416 NM_022167 NP_071450 NR_110010
Function Probably catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes (By similarity). Its enzyme activity has not been demonstrated. {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Expressed at higher level in kidney and pancreas. {ECO:0000269|PubMed:11099377}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

XylT-II (G-1) - sc-374134 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
XylT-II (G-1): sc-374134. Western blot analysis of XylT-II expression in MIA PaCa-2 (A) and Caki-1 (B) whole cell lysates.

XylT-II (N-20) - sc-50876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

XylT-II (C-17) - sc-50874 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-XYLT2 antibody - ab155193 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-XYLT2 antibody (ab155193) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-XYLT2 antibody - ab197296 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-XYLT2 antibody (ab197296) at 1/500 dilution + MDA-MB-231 lysate

Anti-XYLT2 antibody - ab81311 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-XYLT2 antibody (ab81311) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal Muscle Lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-XYLT2 antibody - N-terminal - ab138982 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-XYLT2 antibody - N-terminal (ab138982) at 1/100 dilution + Mouse heart tissue lysates at 35 µgdeveloped using the ECL technique

Anti-XYLT2 Antibody (aa29-58, AP) - LS-C273764 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa29-58, APC) - LS-C273766 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa29-58, Biotin) - LS-C273767 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa29-58, FITC) - LS-C273768 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa29-58, Azide-free, HRP) - LS-C273769 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa28-58) - LS-C326406 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa29-58, PE) - LS-C273770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-XYLT2 Antibody (aa575-624) - LS-C107653 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
XYLT2 antibody LS-C107653 Western blot of HT1080 cell lysate.

Anti-XYLT2 Antibody (aa29-58) - LS-C157383 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
XYLT2 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The XYLT2 antibody detected the XYLT2 protein (arrow).

Anti-XYLT2 Antibody (aa722-771) IHC-plus™ - LS-B8195 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human, Skeletal muscle: Formalin-Fixed Paraffin-Embedded (FFPE)

XYLT2 Antibody - NBP1-87181 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: XYLT2 Antibody [NBP1-87181] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)

XYLT2 Antibody - NBP1-69321 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XYLT2 Antibody - NBP1-33208 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: XYLT2 Antibody [NBP1-33208] - Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE; antibody diluted at 1:1000.

Anti-XYLT2 antibody produced in rabbit - SAB2104844 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-XYLT2, antibody produced in rabbit: <B>Cat. No. SAB2104844</B>: Immunoblotting analysis of XYLT2 in HT1080 cell lysate with XYLT2 anitbody at 1 μg/mL.

Anti-XYLT2 antibody produced in rabbit - HPA016456 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-XYLT2: <B>Cat. No. HPA016456</B>: Immunohistochemical staining of human kidney shows cytoplasmic positivity in renal tubules.

Anti-XYLT2 antibody produced in rabbit - SAB2102730 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XYLT2 antibody - middle region (ARP49702_P050) - ARP49702_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XYLT2 antibody - C-terminal region (ARP49703_P050) - ARP49703_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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