SSTR4

Gene Symbol	SSTR4
Entrez Gene	6754
Alt Symbol	SS-4-R, SS4-R, SS4R
Species	Human
Gene Type	protein-coding
Description	somatostatin receptor 4
Other Description	G-protein coupled receptor\|somatostatin receptor type 4
Swissprots	Q17RM1 Q17RM3 P31391 Q9UIY1
Accessions	AAA36623 AAA60565 AAM22890 AAS55648 BAA04106 CBE74691 CDM63486 EAX10168 EAX10169 EAX10170 P31391 BC069063 AAH69063 BC117270 AAI17271 BC117272 AAI17273 NM_001052 NP_001043
Function	Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.
Top Pathways	Neuroactive ligand-receptor interaction

SSTR4 (H-50) - sc-25678 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

SSTR4 (H-50): sc-25678. Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.

SSTR4 (C-15) - sc-11619 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-Somatostatin Receptor 4 antibody - ab28578 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunofluorescent analysis of Somatostatin Receptor 4 (green) showing staining in the cytoplasm of SH-SY5Y cells (right) compared to a negative control without primary antibody (left). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with a Somatostatin Receptor 4 polyclonal antibody ab28578) in 3% BSA-PBS at a dilution of 1:100 and incubated overnight at 4 ºC in a humidified chamber. Cells were washed with PBST and incubated with a DyLight-conjugated secondary antibody in PBS at room temperature in the dark. F-actin (red) was stained with a flourescent red phalloidin and nuclei (blue) were stained with Hoechst or DAPI. Images were taken at a magnification of 60x.

Anti-Somatostatin Receptor 4 antibody - ab49298 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Lane 1 : Lane 2 : Anti-Somatostatin Receptor 4 antibody (ab49298) at 1.25 µg/mlLane 1 : MW markerLane 2 : Jurkat cell lysate at 10 µgSecondaryLane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Somatostatin Receptor 4 antibody - ab138272 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Somatostatin Receptor 4 antibody (ab138272) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-Somatostatin Receptor 4 antibody - N-terminal - ab140995 from Abcam

Prices	$376.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of Formalin-fixed, Paraffin-Embedded Human pancreas, islet of Langerhans tissue labelling Somatostatin Receptor 4 with ab140995 at 6 µg/ml.

Anti-SSTR4 Antibody (aa145-194) - LS-C200727 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of the lysates from HepG2 cells using SSTR4 antibody.

Anti-SSTR4 Antibody (aa163-212) - LS-C29805 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SSTR4 Antibody (aa163-212) - LS-C30922 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SSTR4 Antibody (aa155-204) - LS-C120952 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of extracts from LOVO cells, using SSTR4 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SSTR4 Antibody (Gln194) - LS-C177412 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of SSTR4 (Q194) pAb in extracts from LOVO cells.

Anti-SSTR4 Antibody (N-Terminus) IHC-plus™ - LS-A4148 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SSTR4 antibody LS-A4148 IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Somatostatin R4/SSTR4 Antibody - NB100-74539 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: Somatostatin R4/SSTR4 Antibody [NB100-74539] - Analysis of 25 ug of HepG2 (lane 1), Jurkat (lane 2) and NIH-3T3 (lane 3) cell lysates.

Somatostatin R4/SSTR4 Antibody - NLS4148 from Novus Biologicals

Prices	$329.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: Somatostatin R4/SSTR4 Antibody [NLS4148] - Analysis of anti-SSTR4 antibody with human brain, glioblastoma.

Somatostatin R4/SSTR4 Antibody - NBP1-01023 from Novus Biologicals

Prices	$349.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: Somatostatin Receptor 4 Antibody [NBP1-01023] - Somatostatin Receptor 4 Antibody Western blot (WB) analysis of SSTR4 (Q194) antibody in extracts from LOVO cells

Somatostatin R4/SSTR4 Antibody - NBP2-39022 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: Somatostatin R4/SSTR4 Antibody [NBP2-39022] - Staining of human stomach shows moderate membrane positivity in glandular cells.

Rabbit Anti-SSTR4 Polyclonal Antibody - bs-1900R from Bioss

Prices	$245.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Somatostatin Receptor Type 4 antibody produced in rabbit - S0945 from Sigma-Aldrich

Prices	$475.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

Anti-SSTR4 antibody produced in rabbit - SAB4502863 from Sigma-Aldrich

Prices	$335.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-SSTR4, N-Terminal: <B>Cat. No. SAB4502863</B>: Immunoblotting analysis of extracts from LOVO cells, using Anti-SSTR4, N-Terminal antibody. The lane on the left was treated with the Anti-SSTR4, N-Terminal antibody. The lane on the right (negative control) was treated with both Anti-SSTR4, N-Terminal antibody and the synthesized immunogen peptide.

SSTR4 antibody - middle region (ARP33359_P050) - ARP33359_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SSTR4 antibody - middle region (ARP33359_T100) - ARP33359_T100 from Aviva Systems Biology

Prices	$229.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SSTR4 Antibody (OAAF05218) - OAAF05218 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

SSTR4 Antibody (OAAF07173) - OAAF07173 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

SSTR4 Polyclonal Antibody - A6988 from ABclonal

Prices	$130.00, $220.00, $380.00
Sizes	50 µl, 100 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using SSTR4 antibody.

SSTR4 antibody (FITC) - orb14250 from Biorbyt

Prices	$315.00
Sizes	100 μg
Host	Rabbit
Clonality	Polyclonal

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