BCKDK

Gene Symbol BCKDK
Entrez Gene 10295
Alt Symbol BCKDKD, BDK
Species Human
Gene Type protein-coding
Description branched chain ketoacid dehydrogenase kinase
Other Description BCKD-kinase|BCKDHKIN|[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial|branched chain alpha-ketoacid dehydrogenase kinase
Swissprots Q96G95 A8MY43 Q96IN5 Q6FGL4 O14874
Accessions EAW52160 EAW52161 EAW52162 EAW52163 EAW52164 O14874 AF026548 AAB82714 AK130145 AK294691 BAG57850 BC007363 AAH07363 BC009872 AAH09872 BM679327 BX427330 CR542093 CAG46890 DQ893687 ABM84613 DQ896864 ABM87863 NM_001122957 NP_001116429 NM_001271926 NP_001258855 NM_005881 NP_005872
Function Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. {ECO:0000269|PubMed:24449431}.
Subcellular Location Mitochondrion matrix. Mitochondrion {ECO:0000269|PubMed:24449431}.
Tissue Specificity Ubiquitous.

BCKDK (E-12) - sc-374425 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BCKDK (E-12): sc-374425. Western blot analysis of BCKDK expression in non-transfected: sc-117752 (A) and human BCKDK transfected: sc-158293 (B) 293T whole cell lysates.

BCKDK (F-10) - sc-374424 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BCKDK (F-10): sc-374424. Western blot analysis of BCKDK expression in non-transfected: sc-117752 (A) and human BCKDK transfected: sc-158293 (B) 293T whole cell lysates.

BCKDK (H-280) - sc-134640 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BCKDK (H-280): sc-134640. Western blot analysis of BCKDK expression in non-transfected: sc-117752 (A) and human BCKDK transfected: sc-158293 (B) 293T whole cell lysates.

BCKDK (T-15) - sc-163735 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BCKDH kinase antibody - ab111716 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-BCKDH kinase antibody (ab111716) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-BCKDH kinase antibody - ab65027 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab65027 at 1/500 - 1/1000 dilution staining BCKDH kinase in HeLa cells by Immunofluorescence, in the absence (-) or presence (+) of the immunising peptide.

Anti-BCKDH kinase antibody [11C9] - ab118038 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 11C9
All lanes : Anti-BCKDH kinase antibody [11C9] (ab118038) at 1/2000 dilutionLane 1 : HEK293T cells transfected with the pCMV6-ENTRY control Lane 2 : HEK293T cells transfected with the pCMV6-ENTRY BCKDH kinase cDNALysates/proteins at 5 µg per lane.

Anti-BCKDH kinase antibody [EPR7564] - ab128935 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7564
All lanes : Anti-BCKDH kinase antibody [EPR7564] (ab128935) at 1/1000 dilutionLane 1 : Fetal kidney lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLane 4 : SH-SY5Y cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilution

Anti-BCKDK Antibody (aa111-160) - LS-C81699 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Fetal brain cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-BCKDK Antibody (Glu41) - LS-C191919 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa159-188, APC) - LS-C252440 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa159-188, AP) - LS-C252439 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa159-188, Biotin) - LS-C252441 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (Internal, clone EPR7564) - LS-C152451 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7564
Western blot analysis on (A) fetal kidney, (B) HeLa, (C) HepG2, and (D) SH-SY5Y cell lysates using anti-BCKDK antibody.

Anti-BCKDK Antibody (aa159-188, FITC) - LS-C252442 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa159-188, Azide-free, HRP) - LS-C252443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (C-Terminus, AP) - LS-C275437 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (N-Terminus) - LS-C146419 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BCKDK antibody LS-C146419 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-BCKDK Antibody (aa159-188, PE) - LS-C252444 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (C-Terminus, APC) - LS-C275438 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (C-Terminus, Biotin) - LS-C275439 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (C-Terminus, FITC) - LS-C275440 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa120-151) - LS-C97773 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-BCKDK Antibody (aa158-188) - LS-C319799 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BCKDK Antibody (aa11-60) - LS-C118664 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of HeLa cells, using BCKD Antibody. The picture on the right is treated with the synthesized peptide.
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