Gene Symbol | BCKDK |
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Entrez Gene | 10295 |
Alt Symbol | BCKDKD, BDK |
Species | Human |
Gene Type | protein-coding |
Description | branched chain ketoacid dehydrogenase kinase |
Other Description | BCKD-kinase|BCKDHKIN|[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial|branched chain alpha-ketoacid dehydrogenase kinase |
Swissprots | Q96G95 A8MY43 Q96IN5 Q6FGL4 O14874 |
Accessions | EAW52160 EAW52161 EAW52162 EAW52163 EAW52164 O14874 AF026548 AAB82714 AK130145 AK294691 BAG57850 BC007363 AAH07363 BC009872 AAH09872 BM679327 BX427330 CR542093 CAG46890 DQ893687 ABM84613 DQ896864 ABM87863 NM_001122957 NP_001116429 NM_001271926 NP_001258855 NM_005881 NP_005872 |
Function | Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. {ECO:0000269|PubMed:24449431}. |
Subcellular Location | Mitochondrion matrix. Mitochondrion {ECO:0000269|PubMed:24449431}. |
Tissue Specificity | Ubiquitous. |
Active cow BCKDH kinase full length protein - ab176939 from Abcam
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Human BCKDH kinase full length protein - ab177577 from Abcam
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BCKDK Antibody Blocking Peptide - LS-E2715 from LifeSpan Bioscience
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BCKDK Antibody Blocking Peptide - LS-E8680 from LifeSpan Bioscience
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BCKDK Antibody Blocking Peptide - LS-E8700 from LifeSpan Bioscience
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BCKDK Antibody Blocking Peptide - LS-E18717 from LifeSpan Bioscience
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Recombinant Human BCKDK Protein - H00010295-P01 from Novus Biologicals
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Recombinant Human BCKDK Protein - H00010295-P02 from Novus Biologicals
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Recombinant Human BCKDK Protein - H00010295-Q01 from Novus Biologicals
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BCKDK Peptide - P2256 from Novus Biologicals
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BCKDK-Antibody-Center-Blocking-Peptide - BP7112a from Abgent, a WuXi AppTec company
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BCKDK-Antibody-C-term-T340-Blocking-Peptide - BP7090b from Abgent, a WuXi AppTec company
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BCKDK peptide - orb218330 from Biorbyt
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BCKDK Blocking Peptide - 33R-1742 from Fitzgerald
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BCKDK Blocking Peptide - abx063661 from Abbexa
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BCKDK - H00010295-P02 from Acris Antibodies
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BCKDK - H00010295-P02-02 from Acris Antibodies
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BCKDK - H00010295-Q01-10 from Acris Antibodies
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BCKDK - H00010295-Q01-25 from Acris Antibodies
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BCKDK fusion protein - ag8371 from Proteintech Group
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BCKDK fusion protein - ag8395 from Proteintech Group
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Recombinant Human BCKDK, His-tagged - BCKDK-27438TH from Creative Biomart
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Recombinant Human BCKDK, GST-tagged - BCKDK-111H from Creative Biomart
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Recombinant Branched Chain Alpha-Ketoacid Dehydrogenase Kinase (BCKDK) - RPJ560Ra01 from Uscn Life Science Inc.
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BCKDK protein-GST fusion - 009-001-R48 from Rockland Immunochemicals Inc
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