E2F6

Gene Symbol	E2F6
Entrez Gene	1876
Alt Symbol	E2F-6
Species	Human
Gene Type	protein-coding
Description	E2F transcription factor 6
Other Description	transcription factor E2F6
Swissprots	Q7Z2H6 Q6Q9Z6 O60544 G5E936 A8K2Z8 O75461 Q53QY9
Accessions	AAM10784 AAM10785 AAT02635 AAY14826 CAD37950 CAD37951 CAD37952 EAX00931 EAX00932 EAX00933 EAX00934 EAX00935 EAX00936 O75461 AF041381 AAC14694 AF059292 AAC31426 AF088059 AK096197 BAG53228 AK223159 BAD96879 AK223407 BAD97127 AK290413 BAF83102 AK293504 BAH11524 AU132447 AU142999 AY083996 AAM10783 AY551346 AAT02636 AY551347 AAT02637 AY551348 AAT02638 AY551349 AAT02639 AY551350 AAT02640 AY551351 AAT02641 BC008348 AAH08348 BC062610 BC107740 AAI07741 BI772069 BQ447956 BU076470 DA609616 XM_011510317 XP_011508619 NM_001278275 NP_001265204 NM_001278276 NP_001265205 NM_001278277 NP_001265206 NM_001278278 NP_001265207 NM_198256 NP_937987 NM_212540 NP_997705 NR_103490 NM_198257 NM_198258 NM_198325
Function	Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
Subcellular Location	Nucleus.
Tissue Specificity	Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human E2F6 full length protein - ab114573 from Abcam Category Protein Source Wheat germ Species Human

E2F6 Antibody Blocking Peptide - LS-E22488 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

E2F6 Antibody Blocking Peptide - LS-E11260 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

E2F6 Antibody Blocking Peptide - LS-E27089 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human E2F6 Protein - H00001876-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

E2F6 blocking peptide - GTX88255-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Bovine

E2F6 Blocking Peptide - abx062555 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

E2F6 Peptide - AC21-1911-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

E2F6 - H00001876-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

E2F6 - H00001876-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

E2F6 Peptide - 42-237P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

E2F6 fusion protein - ag1029 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human E2F6 - E2F6-26508TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human E2F6, GST-tagged - E2F6-12249H from Creative Biomart Category Protein Source E.coli Species Human

E2F6 Blocking Peptide - CBP1361 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

E2F-6 (E170) Peptide - BS1096P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Transcription factor E2F6(E2F6) - CSB-YP007347HU CSB-EP007347HU CSB-BP007347HU CSB-MP007347HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

E2F6, Peptide - MBS426981 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Dog, Bovine

E2F6-Antibody-Center-Blocking-Peptide - BP6637c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

E2F6 Peptide, Human - M34GP04669H from Creative Peptides Category Peptide Source Synthetic. Species Human

E2F6 Recombinant Protein Antigen - NBP2-56043PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

E2F6 Recombinant Protein (Human) (OPCA04778) - OPCA04778 from Aviva Systems Biology Category Protein Species Human

Recombinant Human Transcription factor E2F6 (E2F6) - RPC21235 from Biomatik Category Protein Prices $276.00, $505.00, $2,491.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

E2F6 Immunizing peptide - orb15215 from Biorbyt Category Peptide

E2F6 peptide - orb217224 from Biorbyt Category Peptide Species Human, Mouse, Rat

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