CACNG8

Gene Symbol CACNG8
Entrez Gene 59283
Alt Symbol -
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, gamma subunit 8
Other Description TARP gamma-8|neuronal voltage-gated calcium channel gamma-8 subunit|transmembrane AMPAR regulatory protein gamma-8|voltage-dependent calcium channel gamma-8 subunit
Swissprots Q9BXT0 Q8WXS5 Q9BY23
Accessions EAW72168 Q8WXS5 AF234892 AAK15019 AF288388 AAK20031 AF361354 AAL50049 AK055160 AK131287 BC157119 AAI57120 BC172268 AAI72268 NM_031895 NP_114101
Function Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. {ECO:0000269|PubMed:20805473, ECO:0000269|PubMed:21172611}.
Subcellular Location Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}.
Top Pathways MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

L-type Ca ++ CP γ8 CRISPR/Cas9 KO Plasmid (h) - sc-407391 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 HDR Plasmid (h) - sc-407391-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 Double Nickase Plasmid (h) - sc-407391-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 Double Nickase Plasmid (h2) - sc-407391-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 CRISPR Activation Plasmid (h) - sc-407391-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 CRISPR Activation Plasmid (h2) - sc-407391-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 Lentiviral Activation Particles (h) - sc-407391-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 Lentiviral Activation Particles (h2) - sc-407391-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca ++ CP γ8 siRNA (h) - sc-97586 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

L-type Ca ++ CP γ8 shRNA Plasmid (h) - sc-97586-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

L-type Ca ++ CP γ8 shRNA (h) Lentiviral Particles - sc-97586-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN5280 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CACNG8 siRNA (Human) - CRJ1764 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CACNG8 RNAi - H00059283-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CACNG8 - MBS8201606 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CACNG8 (NM_031895.5) - SHH253549 from Creative biogene

Category siRNA
Species Reactivities Human

L-type Ca++ CP γ8 CRISPR/Cas9 KO Plasmid (h2) - sc-407391-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

L-type Ca++ CP γ8 HDR Plasmid (h2) - sc-407391-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human CACNG8 siRNA - orb272265 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CACNG8 shRNA Plasmid (Human) - CHJ1764 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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