CD164

Gene Symbol CD164
Entrez Gene 8763
Alt Symbol MGC-24, MUC-24, endolyn
Species Human
Gene Type protein-coding
Description CD164 molecule, sialomucin
Other Description CD164 antigen, sialomucin|CD164 variant C|MGC-24v|multi-glycosylated core protein 24|sialomucin core protein 24
Swissprots Q9BPV0 O95413 Q9NR26 E1P5E9 Q04900 E1P5E7 Q5JSU6 B4DQ85 E1P5E8
Accessions AAG53903 AAG53904 AAG53905 CDM22287 EAW48348 EAW48349 EAW48350 EAW48351 EAW48352 EAW48353 EAW48354 EAW48355 Q04900 AF106518 AAC82473 AF263279 AAF85965 AF299341 AAG53906 AF299342 AAG53907 AF299343 AAG53908 AK298684 BAG60847 AK301692 BAG63164 AK303525 BAG64553 AK307193 AK308664 AK310854 AK312357 BAG35275 AK315908 BAH14279 BC011522 AAH11522 BC037914 BC040317 BM668503 BM817924 BM830140 D14043 BAA03130 DC403839 DQ891034 ABM81960 DQ894213 ABM85139 EB388947 FJ200494 ACO54891 NM_001142401 NP_001135873 NM_001142402 NP_001135874 NM_001142403 NP_001135875 NM_001142404 NP_001135876 NM_006016 NP_006007
Function Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity). {ECO:0000250}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}. Endosome membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}. Cell membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}.
Tissue Specificity Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells. {ECO:0000269|PubMed:10878358, ECO:0000269|PubMed:11027692, ECO:0000269|PubMed:1478919, ECO:0000269|PubMed:16859559, ECO:0000269|PubMed:9763543}.
Top Pathways Lysosome

CD164 (H-4) - sc-271179 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD164 (H-4): sc-271179. Western blot analysis of CD164 expression in COLO 320DM whole cell lysate.

CD164 (H-123) - sc-33124 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CD164 (FL-189): sc-33124. Western blot analysis of CD164 expression in T-47D (A), HL-60 (B), K-562 (C) and HEL 92.1.7 (D) whole cell lysates.

CD164 (N-15) - sc-27799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CD164 antibody - ab57948 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CD164 antibody (ab57948) + immunogenObserved band size : 35 kDa (why is the actual band size different from the predicted?)

Anti-CD164 antibody [67D2] - ab66982 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 67D2

Anti-CD164 Antibody (clone 3D7) - LS-C139380 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D7

Anti-CD164 Antibody (aa1-115) - LS-C306803 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CD164 Antibody (clone 67D2, FITC) - LS-C179628 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 67D2

Anti-CD164 Antibody (clone 67D2) - LS-C179627 from LifeSpan Bioscience

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 67D2

CD164 Antibody [Unconjugated] - AF5790 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

CD164 Antibody (502021) [Unconjugated] - MAB5790 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 502021
CXCL12-treated PC‑3 human prostate cancer cell line was stained with Mouse Anti-Human CD164 Monoclonal Antibody (Catalog # MAB5790, filled histogram) or isotype control antibody (Catalog # MAB007, open histogram), followed by APC-conjugated anti-mouse antibody (Catalog # F0101B).

CD164 Antibody - NBP1-81159 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CD164 Antibody (3D7) - H00008763-M11 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D7

CD164 Antibody (4B4) - H00008763-M10 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B4

CD164 Antibody - H00008763-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

CD164 Antibody [Biotin] - BAF5790 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Anti-CD164 antibody produced in rabbit - HPA010636 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CD164: <B>Cat. No. HPA010636</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells.

Monoclonal Anti-CD164 antibody produced in mouse - WH0008763M10 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B4
<B>Immunoblotting</B><BR/>Monoclonal Anti-CD164, <B>Cat. No. WH0008763M10</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.65 kDa using immunogen protein lysate.

Monoclonal Anti-CD164 antibody produced in mouse - C9618 from Sigma-Aldrich

Prices $63.50, $413.50
Sizes 25 µl, 200 µl
Host Mouse
Clonality Monoclonal
Clone 67D2

Monoclonal Anti-CD164 antibody produced in mouse - SAB1404619 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D7
<B>Immunoblotting</B><BR/>Monoclonal Anti-CD164: <B>Cat. No. SAB1404619</B>: Antibody concentration: 1 μg/mL. Specific band of ~47.8 kDa using immunogen protein lysate.

CD164-Antibody-C-term - AP21047a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from K562, LNCaP, PC-3 cell line, mouse brain, mouse kidney, rat liver tissue lysate (from left to right), using CD164 Antibody (C-term)(Cat. #AP21047a). AP21047a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Human CD164 Antibody - AF5790 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Detection of Human CD164 by Western Blot. Western blot shows lysates of U937 human histiocytic lymphoma cell line and human peripheral blood mononuclear cells (PBMC). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human CD164 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5790) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016 ). A specific band was detected for CD164 at approximately XXX kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group XXX .

Human CD164 Affinity Purified Polyclonal Ab, Sheep IgG - AF5790-SP from R&D Systems

Host Sheep
Clonality Polyclonal
Detection of Human CD164 by Western Blot. Western blot shows lysates of U937 human histiocytic lymphoma cell line and human peripheral blood mononuclear cells (PBMC). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human CD164 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5790) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for CD164 at approximately XXX kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group XXX.

Mouse CD164 Antibody - AF3118 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat

Mouse CD164 Affinity Purified Polyclonal Ab, Goat IgG - AF3118-SP from R&D Systems

Host Goat
Clonality Polyclonal
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