CD164

Gene Symbol CD164
Entrez Gene 8763
Alt Symbol MGC-24, MUC-24, endolyn
Species Human
Gene Type protein-coding
Description CD164 molecule, sialomucin
Other Description CD164 antigen, sialomucin|CD164 variant C|MGC-24v|multi-glycosylated core protein 24|sialomucin core protein 24
Swissprots Q9BPV0 O95413 Q9NR26 E1P5E9 Q04900 E1P5E7 Q5JSU6 B4DQ85 E1P5E8
Accessions AAG53903 AAG53904 AAG53905 CDM22287 EAW48348 EAW48349 EAW48350 EAW48351 EAW48352 EAW48353 EAW48354 EAW48355 Q04900 AF106518 AAC82473 AF263279 AAF85965 AF299341 AAG53906 AF299342 AAG53907 AF299343 AAG53908 AK298684 BAG60847 AK301692 BAG63164 AK303525 BAG64553 AK307193 AK308664 AK310854 AK312357 BAG35275 AK315908 BAH14279 BC011522 AAH11522 BC037914 BC040317 BM668503 BM817924 BM830140 D14043 BAA03130 DC403839 DQ891034 ABM81960 DQ894213 ABM85139 EB388947 FJ200494 ACO54891 NM_001142401 NP_001135873 NM_001142402 NP_001135874 NM_001142403 NP_001135875 NM_001142404 NP_001135876 NM_006016 NP_006007
Function Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity). {ECO:0000250}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}. Endosome membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}. Cell membrane {ECO:0000269|PubMed:11027692}; Single-pass type I membrane protein {ECO:0000269|PubMed:11027692}.
Tissue Specificity Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells. {ECO:0000269|PubMed:10878358, ECO:0000269|PubMed:11027692, ECO:0000269|PubMed:1478919, ECO:0000269|PubMed:16859559, ECO:0000269|PubMed:9763543}.
Top Pathways Lysosome

CD164 CRISPR/Cas9 KO Plasmid (h) - sc-404397 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 HDR Plasmid (h) - sc-404397-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 Double Nickase Plasmid (h) - sc-404397-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 Double Nickase Plasmid (h2) - sc-404397-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 CRISPR Activation Plasmid (h) - sc-404397-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 CRISPR Activation Plasmid (h2) - sc-404397-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 Lentiviral Activation Particles (h) - sc-404397-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 Lentiviral Activation Particles (h2) - sc-404397-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD164 siRNA (h) - sc-44677 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD164 shRNA Plasmid (h) - sc-44677-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD164 shRNA (h) Lentiviral Particles - sc-44677-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD164 RNAi - H00008763-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU065691 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5684 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5684 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00004 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00004

CD164 siRNA (Human) - CRH5772 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD164 - MBS8234042 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD164 (NM_006016.4) - SHH258521 from Creative biogene

Category siRNA
Species Reactivities Human

Human CD164 siRNA - orb266274 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD164 shRNA Plasmid (Human) - CHH5772 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD164 miRNA 3'UTR clone - MiUTR3H-05886 from Creative biogene

Species Reactivities Human

CD164 miRNA 3'UTR clone - MiUTR3H-05887 from Creative biogene

Species Reactivities Human

CD164 miRNA 3'UTR clone - MiUTR4H-TG01867 from Creative biogene

Species Reactivities Human
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