HERC3

Gene Symbol HERC3
Entrez Gene 8916
Alt Symbol -
Species Human
Gene Type protein-coding
Description HECT and RLD domain containing E3 ubiquitin protein ligase 3
Other Description HECT domain and RCC1-like domain-containing protein 3|hect domain and RLD 3|probable E3 ubiquitin-protein ligase HERC3
Swissprots A8K1S5 Q8IXX3 Q15034
Accessions AAY41038 EAX06024 Q15034 AK289990 BAF82679 AK296379 BAG59053 AK296397 BAG59064 BC038960 AAH38960 BC166672 AAI66672 BE044624 BE044630 BQ925135 D25215 BAA04945 DA333248 XM_005263327 XP_005263384 XM_005263329 XP_005263386 XM_005263330 XP_005263387 XM_005263331 XP_005263388 XM_005263332 XP_005263389 XM_011532397 XP_011530699 NM_001271602 NP_001258531 NM_014606 NP_055421
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
Subcellular Location Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
Top Pathways Ubiquitin mediated proteolysis

Herc3 (37.2) - sc-100720 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Herc3 (37.2): sc-100720. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas tissue showing cytoplasmic localization.

Anti-HERC3 antibody - ab100908 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HERC3 antibody (ab100908) at 1/500 dilutionLane 1 : PANC-1 Cell LysateLane 2 : Human Fetal Heart Lysate

Anti-HERC3 antibody - ab56440 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
HERC3 antibody (ab56440) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human pancreas.

Anti-HERC3 antibody - ab172284 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HERC3 antibody (ab172284) at 1 µg/mlLane 1 : HERC3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/7500 dilution

Anti-HERC3 antibody - ab172309 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HERC3 antibody (ab172309) at 1 µg/mlLane 1 : Lysate from 293T cells transfected with HERC3Lane 2 : Lysate from untransfected 293T cellsLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HERC3 antibody - N-terminal - ab174252 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HERC3 antibody - N-terminal (ab174252) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-HERC3 Antibody (aa51-77, AP) - LS-C258417 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa51-77, APC) - LS-C258418 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa51-77, Biotin) - LS-C258419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa51-77, FITC) - LS-C258420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa51-77, Azide-free, HRP) - LS-C258421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa51-77, PE) - LS-C258423 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (clone 2C1) - LS-C104905 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C1
Detection limit for recombinant GST tagged HERC3 is approximately 0.1 ng/ml as a capture antibody.

Anti-HERC3 Antibody - LS-C310593 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa251-300) - LS-C201443 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human ACHN. HERC3 antibody dilution 1.0 ug/ml.

Anti-HERC3 Antibody (aa51-77) - LS-C321928 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERC3 Antibody (aa1-110, Azide-free) - LS-C327540 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-HERC3 Antibody (aa51-77) - LS-C157803 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HERC3 Antibody western blot of K562 cell line lysates (35 ug/lane). The HERC3 antibody detected the HERC3 protein (arrow).

HERC3 Antibody - NBP1-81553 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HERC3 Antibody [NBP1-81553] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

HERC3 Antibody (2C1) - H00008916-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C1

HERC3 Antibody - H00008916-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HERC3 Antibody [H00008916-D01P] - Analysis of HERC3 expression in transfected 293T cell line by HERC3 polyclonal antibody.Lane 1: HERC3 transfected lysate(117.20 KDa).Lane 2: Non-transfected lysate.

HERC3 Antibody - H00008916-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HERC3 Antibody [H00008916-B01] - analysis of HERC3 expression in transfected 293T cell line by HERC3 MaxPab polyclonal antibody (B01). Lane1: HERC3 transfected lysate (117.20 KDa). Lane2: Non-transfected lysate.

HERC3 Antibody - H00008916-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

HERC3 Antibody (3G7) - H00008916-M02 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G7

HERC3 Antibody (2C1) - H00008916-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2C1
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