Gene Symbol | HERC3 |
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Entrez Gene | 8916 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
Other Description | HECT domain and RCC1-like domain-containing protein 3|hect domain and RLD 3|probable E3 ubiquitin-protein ligase HERC3 |
Swissprots | A8K1S5 Q8IXX3 Q15034 |
Accessions | AAY41038 EAX06024 Q15034 AK289990 BAF82679 AK296379 BAG59053 AK296397 BAG59064 BC038960 AAH38960 BC166672 AAI66672 BE044624 BE044630 BQ925135 D25215 BAA04945 DA333248 XM_005263327 XP_005263384 XM_005263329 XP_005263386 XM_005263330 XP_005263387 XM_005263331 XP_005263388 XM_005263332 XP_005263389 XM_011532397 XP_011530699 NM_001271602 NP_001258531 NM_014606 NP_055421 |
Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}. |
Subcellular Location | Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures. |
Top Pathways | Ubiquitin mediated proteolysis |
Herc3 CRISPR/Cas9 KO Plasmid (h) - sc-411227 from Santa Cruz Biotechnology
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Herc3 HDR Plasmid (h) - sc-411227-HDR from Santa Cruz Biotechnology
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Herc3 Double Nickase Plasmid (h) - sc-411227-NIC from Santa Cruz Biotechnology
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Herc3 Double Nickase Plasmid (h2) - sc-411227-NIC-2 from Santa Cruz Biotechnology
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Herc3 CRISPR Activation Plasmid (h) - sc-411227-ACT from Santa Cruz Biotechnology
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Herc3 CRISPR Activation Plasmid (h2) - sc-411227-ACT-2 from Santa Cruz Biotechnology
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Herc3 Lentiviral Activation Particles (h) - sc-411227-LAC from Santa Cruz Biotechnology
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Herc3 Lentiviral Activation Particles (h2) - sc-411227-LAC-2 from Santa Cruz Biotechnology
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Herc3 siRNA (h) - sc-89133 from Santa Cruz Biotechnology
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Herc3 shRNA Plasmid (h) - sc-89133-SH from Santa Cruz Biotechnology
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Herc3 shRNA (h) Lentiviral Particles - sc-89133-V from Santa Cruz Biotechnology
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HERC3 RNAi - H00008916-R01 from Novus Biologicals
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MISSION® esiRNA - EHU006951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9984 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9984 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09805 from Sigma-Aldrich
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HERC3 siRNA (Human) - CRH5898 from Cohesion Biosciences
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HERC3 - MBS8234596 from MyBioSource
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shRNA set against Human HERC3 (NM_014606.2) - SHH311613 from Creative biogene
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Human HERC3 siRNA - orb266400 from Biorbyt
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HERC3 shRNA Plasmid (Human) - CHH5898 from Cohesion Biosciences
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HERC3 miRNA 3'UTR clone - MiUTR3H-07450 from Creative biogene
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