Gene Symbol |
HERC3
|
Entrez Gene |
8916
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
HECT and RLD domain containing E3 ubiquitin protein ligase 3
|
Other Description |
HECT domain and RCC1-like domain-containing protein 3|hect domain and RLD 3|probable E3 ubiquitin-protein ligase HERC3
|
Swissprots |
A8K1S5 Q8IXX3 Q15034
|
Accessions |
AAY41038 EAX06024 Q15034 AK289990 BAF82679 AK296379 BAG59053 AK296397 BAG59064 BC038960 AAH38960 BC166672 AAI66672 BE044624 BE044630 BQ925135 D25215 BAA04945 DA333248 XM_005263327 XP_005263384 XM_005263329 XP_005263386 XM_005263330 XP_005263387 XM_005263331 XP_005263388 XM_005263332 XP_005263389 XM_011532397 XP_011530699 NM_001271602 NP_001258531 NM_014606 NP_055421
|
Function |
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
|
Subcellular Location |
Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
|
Top Pathways |
Ubiquitin mediated proteolysis
|