ASAP1

Gene Symbol	ASAP1
Entrez Gene	50807
Alt Symbol	AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P
Species	Human
Gene Type	protein-coding
Description	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Other Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein|130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein|ADP-ribosylation factor-directed GTPase-activating protein 1|ARF GTPase-activating protein 1|DEF-1|PIP2-dependent ARF1 GAP|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1|centaurin, beta 4|development and differentiation-enhancing factor 1
Swissprots	B2RNV3 Q9ULH1
Accessions	CBX47524 CCQ43599 EAW92130 EAW92131 Q9ULH1 AB033075 BAA86563 AF222859 AAF67666 AI494058 AI656533 AK056811 AK314695 AW236866 AW236958 BC020631 AAH20631 BC070268 BC105978 BC137135 AAI37136 BC144493 BX537768 CAD97831 DA319233 XM_005250925 XP_005250982 XM_006716563 XP_006716626 XM_006716564 XP_006716627 XM_006716565 XP_006716628 XM_006716566 XP_006716629 XM_006716567 XP_006716630 XM_011517052 XP_011515354 XM_011517053 XP_011515355 NM_001247996 NP_001234925 NM_018482 NP_060952
Function	Possesses phosphatidylinositol 4,5-bisphosphate- dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis. {ECO:0000250, ECO:0000269|PubMed:20393563}.
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Predominantly cytoplasmic. Partially membrane- associated. {ECO:0000250}.
Top Pathways	Fc gamma R-mediated phagocytosis, Endocytosis

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• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ASAP1 293 Cell Lysate - 406312 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

ASAP1 Overexpression Lysate (Native) - NBL1-09767 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

ASAP1 Over-expression Lysate Product - GWB-978BA4 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Panoply™ Human ASAP1 Knockdown Stable Cell Line - CSC-DC001006 from Creative biogene Category Cell Line Species Human

Human ASAP1 Knockout Cell Line-HeLa - CSC-RT1704 from Creative biogene Category Cell Line Species Human

ASAP1 KO Cell Lysate-HeLa - CLKO-1551 from Creative biogene Category Cell Lysate

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