ASAP1

Gene Symbol ASAP1
Entrez Gene 50807
Alt Symbol AMAP1, CENTB4, DDEF1, PAG2, PAP, ZG14P
Species Human
Gene Type protein-coding
Description ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Other Description 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein|130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein|ADP-ribosylation factor-directed GTPase-activating protein 1|ARF GTPase-activating protein 1|DEF-1|PIP2-dependent ARF1 GAP|arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1|centaurin, beta 4|development and differentiation-enhancing factor 1
Swissprots B2RNV3 Q9ULH1
Accessions CBX47524 CCQ43599 EAW92130 EAW92131 Q9ULH1 AB033075 BAA86563 AF222859 AAF67666 AI494058 AI656533 AK056811 AK314695 AW236866 AW236958 BC020631 AAH20631 BC070268 BC105978 BC137135 AAI37136 BC144493 BX537768 CAD97831 DA319233 XM_005250925 XP_005250982 XM_006716563 XP_006716626 XM_006716564 XP_006716627 XM_006716565 XP_006716628 XM_006716566 XP_006716629 XM_006716567 XP_006716630 XM_011517052 XP_011515354 XM_011517053 XP_011515355 NM_001247996 NP_001234925 NM_018482 NP_060952
Function Possesses phosphatidylinositol 4,5-bisphosphate- dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis. {ECO:0000250, ECO:0000269|PubMed:20393563}.
Subcellular Location Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Predominantly cytoplasmic. Partially membrane- associated. {ECO:0000250}.
Top Pathways Fc gamma R-mediated phagocytosis, Endocytosis

DDEF1 CRISPR/Cas9 KO Plasmid (h) - sc-406473 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 HDR Plasmid (h) - sc-406473-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 Double Nickase Plasmid (h) - sc-406473-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 Double Nickase Plasmid (h2) - sc-406473-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 CRISPR Activation Plasmid (h) - sc-406473-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 CRISPR Activation Plasmid (h2) - sc-406473-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 Lentiviral Activation Particles (h) - sc-406473-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 Lentiviral Activation Particles (h2) - sc-406473-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DDEF1 siRNA (h) - sc-62196 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDEF1 shRNA Plasmid (h) - sc-62196-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DDEF1 shRNA (h) Lentiviral Particles - sc-62196-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ASAP1 RNAi - H00050807-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU068851 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3562 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3562 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11632 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11632

ASAP1 siRNA (Human) - CRH9406 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ASAP1 - MBS8230231 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ASAP1 (NM_018482.3) - SHH241094 from Creative biogene

Category siRNA
Species Reactivities Human

ASAP1 shRNA Plasmid (Human) - CHH9406 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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